Madhusudhana Reddy P, Hsieh Shih-Rong, Chen Jem-Kun, Chang Chi-Jung, Kang Jing-Yuan, Chen Chih-Hsien
Department of Chemical Engineering, Feng Chia University, 100, Wenhwa Road, Seatwen, Taichung 40724, Taiwan, ROC.
Department of Surgery, Taichung Veterans General Hospital, 1650 Taiwan Boulevard Section 4, Taichung 40705, Taiwan, ROC.
Spectrochim Acta A Mol Biomol Spectrosc. 2017 Nov 5;186:8-16. doi: 10.1016/j.saa.2017.06.004. Epub 2017 Jun 6.
Sensing of F, CN and Ac is important from the viewpoint of both medically and environmentally. Particularly, sensing of the anions in 100% water by a colorimetric chemical sensor is a highly difficult task as water molecules interfere the sensing mechanism. In this regard, sensor R1, having azo and nitrophenyl groups as signaling units and thiourea as a binding site was prepared. This sensor exclusively detected CN ion over other testing anions in 30% aq. DMSO solution by exhibiting distinct spectral and visual color changes. However, in 15% aq. DMSO solution, R1 exhibited obvious spectral and color changes in response to F, CN and Ac. On the other hand, we have also designed sensor, R2, having same signaling units of R1, but a different binding site of urea group. Surprisingly, in contrast to R1, R2 exhibited obvious spectral and color changes in 5% aq. DMSO solution only. Further, economically viable "test stripes" were prepared in a facile mode to detect the CN in 100% aqueous solution. Such stripes can serve as a practical colorimetric probe for "in the field" detection of the ions and thus avoid additional expensive equipment.
从医学和环境角度来看，对氟离子（F⁻）、氰根离子（CN⁻）和醋酸根离子（Ac⁻）的传感都很重要。特别是，利用比色化学传感器在纯水中传感这些阴离子是一项极具挑战性的任务，因为水分子会干扰传感机制。在这方面，制备了以偶氮基和硝基苯基作为信号单元、硫脲作为结合位点的传感器R1。该传感器在30%的二甲基亚砜水溶液中，相对于其他测试阴离子，能通过呈现明显的光谱和视觉颜色变化专门检测氰根离子。然而，在15%的二甲基亚砜水溶液中，R1对氟离子、氰根离子和醋酸根离子都呈现出明显的光谱和颜色变化。另一方面，我们还设计了传感器R2，它具有与R1相同的信号单元，但结合位点是脲基。令人惊讶的是，与R1不同，R2仅在5%的二甲基亚砜水溶液中呈现出明显的光谱和颜色变化。此外，还以简便的方式制备了经济可行的“测试条”，用于检测100%水溶液中的氰根离子。这种测试条可作为一种实用的比色探针用于现场检测离子，从而避免使用额外的昂贵设备。
