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急性脑功能衰竭:谵妄的病理生理学、诊断、管理及后遗症

Acute Brain Failure: Pathophysiology, Diagnosis, Management, and Sequelae of Delirium.

作者信息

Maldonado José R

机构信息

Psychosomatic Medicine Service, Emergency Psychiatry Service, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Suite 2317, Stanford, CA 94305-5718, USA.

出版信息

Crit Care Clin. 2017 Jul;33(3):461-519. doi: 10.1016/j.ccc.2017.03.013.

DOI:10.1016/j.ccc.2017.03.013
PMID:28601132
Abstract

Delirium is the most common psychiatric syndrome found in the general hospital setting, with an incidence as high as 87% in the acute care setting. Delirium is a neurobehavioral syndrome caused by the transient disruption of normal neuronal activity secondary to systemic disturbances. The development of delirium is associated with increased morbidity, mortality, cost of care, hospital-acquired complications, placement in specialized intermediate and long-term care facilities, slower rate of recovery, poor functional and cognitive recovery, decreased quality of life, and prolonged hospital stays. This article discusses the epidemiology, known etiological factors, presentation and characteristics, prevention, management, and impact of delirium.

摘要

谵妄是综合医院环境中最常见的精神综合征,在急性护理环境中的发病率高达87%。谵妄是一种由全身紊乱继发的正常神经元活动短暂中断引起的神经行为综合征。谵妄的发生与发病率增加、死亡率上升、护理成本、医院获得性并发症、入住专门的中长期护理机构、恢复速度减慢、功能和认知恢复不良、生活质量下降以及住院时间延长有关。本文讨论了谵妄的流行病学、已知病因、表现和特征、预防、管理及影响。

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