Igenomix, Parc Cientific Valencia University, Valencia, Spain.
Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas.
Fertil Steril. 2017 Jul;108(1):4-8. doi: 10.1016/j.fertnstert.2017.05.030. Epub 2017 Jun 7.
The embryo alone, though very important, is not sufficient to explain successful or failed implantation. Human embryonic implantation is less efficient than in nonmenstruating species. The main difference lies in the decidual control of early implantation events and the subsequent course of pregnancy versus embryo control in nonmenstruating species. In this article, we introduce the facts behind the low efficiency of this crucial process, address urban legends routinely considered without high clinical quality evidence, and provide a vision of how the endometrial field will develop in the near future.
胚胎本身虽然非常重要,但不足以解释着床的成功或失败。人类胚胎着床的效率不如非经期物种高。主要的区别在于早期着床事件和随后的妊娠过程是由蜕膜控制,而不是非经期物种中的胚胎控制。在本文中,我们介绍了这个关键过程效率低下的背后的事实,讨论了一些没有高质量临床证据支持的常规观点,并对子宫内膜领域在不久的将来如何发展提出了展望。