Wu Jianhui, Sun Xiaofang, Wang Li, Zhang Liang, Fernández Guillén, Yao Zhuxi
Shenzhen Key Laboratory of Affective and Social Cognitive Science, Shenzhen University, Shenzhen, China.
CAS Key Laboratory of Behavioral Science, Institute of Psychology, Beijing, China; University of Chinese Academy of Sciences, Beijing, China.
Psychoneuroendocrinology. 2017 Sep;83:84-90. doi: 10.1016/j.psyneuen.2017.05.029. Epub 2017 Jun 4.
There are substantial individual differences in the response towards acute stressor. The aim of the current study was to examine how the neural activity after an error response during a non-stressful state, prospectively predicts the magnitude of physiological stress response (e.g., cortisol response and heart rate) and negative affect elicited by a laboratory stress induction procedure in nonclinical participants. Thirty-seven healthy young male adults came to the laboratory for the baseline neurocognitive measurement on the first day during which they performed a Go/Nogo task with their electroencephalogram recorded. On the second day, they came again to be tested on their stress response using an acute psychosocial stress procedure (i.e., the Trier Social Stress Test, the TSST). Results showed that the amplitude of error positivity (Pe) significantly predicted both the heart rate and cortisol response towards the TSST. Our results suggested that baseline cognitive neural activity reflecting error consciousness could be used as a biological predictor of physiological response to an acute psychological stressor in men.
个体对急性应激源的反应存在显著差异。本研究的目的是探讨在非应激状态下错误反应后的神经活动如何前瞻性地预测非临床参与者在实验室应激诱导程序中所引发的生理应激反应（如皮质醇反应和心率）的程度以及负面影响。37名健康的年轻男性成年人在第一天来到实验室进行基线神经认知测量，在此期间他们进行了一项“走/停”任务并记录脑电图。第二天，他们再次前来，通过急性心理社会应激程序（即特里尔社会应激测试，TSST）测试其应激反应。结果表明，错误正波（Pe）的幅度显著预测了对TSST的心率和皮质醇反应。我们的结果表明，反映错误意识的基线认知神经活动可作为男性对急性心理应激源生理反应的生物学预测指标。
