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推进转移性乳腺癌研究的障碍、机遇和重点。

Obstacles, Opportunities and Priorities for Advancing Metastatic Breast Cancer Research.

机构信息

Breast Cancer Research Foundation, New York, New York.

Susan G. Komen, Dallas, Texas.

出版信息

Cancer Res. 2017 Jul 1;77(13):3386-3390. doi: 10.1158/0008-5472.CAN-17-0232. Epub 2017 Jun 10.

Abstract

In January 2016, the Metastatic Breast Cancer Alliance (the Alliance) convened a think tank of stakeholders from academia, government, industry, and patient advocacy to discuss gaps and opportunities in clinical and translational research in metastatic breast cancer. Priorities that emerged from the meeting included the following: the need for innovative preclinical model systems to study metastatic disease; increased sharing of resources and data; collaboration across cancer care teams and scientists; biorepositories for studies to identify biomarkers for treatment response; creation of patient registries to increase access to clinical trials and tissue procurement; and redesign of clinical trials in metastatic breast cancer. .

摘要

2016 年 1 月,转移性乳腺癌联盟(联盟)召集了来自学术界、政府、工业界和患者权益倡导组织的利益相关者的智库,讨论转移性乳腺癌临床和转化研究中的差距和机遇。会议提出的优先事项包括以下内容:需要创新的临床前模型系统来研究转移性疾病;增加资源和数据的共享;癌症护理团队和科学家之间的合作;生物库用于研究确定治疗反应的生物标志物;创建患者登记处以增加临床试验和组织采购的机会;以及重新设计转移性乳腺癌的临床试验。

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