胸腺大细胞神经内分泌癌——一种罕见的侵袭性肿瘤：病例报告
Thymic large cell neuroendocrine carcinoma - a rare and aggressive tumor: a case report.
作者信息
Boubacar Efared, Atsame-Ebang Gabrielle, Rabiou Sani, Fatimazahra Ammor, Mazti Asmae, Sidibé Ibrahim S, Tahiri Layla, Hammas Nawal, Yassine Ouadnouni, Mohamed Smahi, Laila Chbani, Hinde El Fatemi
机构信息
Department of Pathology, Hassan II University Hospital, Fès, Morocco.
Department of Thoracic Surgery, Hassan II University Hospital, Fès, Morocco.
出版信息
J Med Case Rep. 2017 Jun 12;11(1):155. doi: 10.1186/s13256-017-1331-2.
BACKGROUND
Neuroendocrine tumors are a large group of tumors with a wide spectrum of behavior, affecting mainly the digestive system and the lung. The thymus is very rarely affected.
CASE PRESENTATION
A 28-year-old Arab woman presented with chronic chest pain and dyspnea. A computed tomography scan showed a huge anterior mediastinal mass invading neighboring structures. A mediastinotomy was performed with biopsies of the mass. Pathological findings were consistent with a thymic large cell neuroendocrine carcinoma.
CONCLUSIONS
The occurrence of a large cell neuroendocrine carcinoma in the thymus, especially in young people, is extremely rare. In this current report, we discuss the clinicopathological issues of this rare tumor according to recent literature data.
背景
神经内分泌肿瘤是一大类行为谱广泛的肿瘤，主要影响消化系统和肺部。胸腺很少受累。
病例报告
一名28岁的阿拉伯女性因慢性胸痛和呼吸困难就诊。计算机断层扫描显示前纵隔有一个巨大肿块，侵犯了邻近结构。进行了纵隔切开术并对肿块进行活检。病理结果与胸腺大细胞神经内分泌癌一致。
结论
胸腺中发生大细胞神经内分泌癌，尤其是在年轻人中，极为罕见。在本报告中，我们根据最近的文献数据讨论了这种罕见肿瘤的临床病理问题。
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