Worthing Robert M, Percy Raechel L, Joslin Jeremy D
Physical Medicine and Rehabilitation Service, Veterans Affairs Medical Center, Lexington, KY (Dr Worthing).
Department of Physical Medicine and Rehabilitation, University of Kentucky, Lexington, KY (Dr Percy).
Wilderness Environ Med. 2017 Jun;28(2):139-149. doi: 10.1016/j.wem.2017.03.007.
The purpose of this systematic review was to determine if sock, antiperspirant, or barrier strategies were effective in prevention of friction blisters in wilderness and outdoor pursuits. A search of PubMed and EMBASE was conducted. Title, abstract, and full text articles were screened by 2 authors using predetermined inclusion and exclusion criteria to identify prospective controlled trials investigating prevention methods for friction blisters involving the foot. Only blisters associated with wilderness and outdoor pursuits (running, hiking, marching, etc.) were considered. Extraction of a predetermined data set was accomplished using a piloted form. Confidence in effect estimates were determined utilizing the Scottish Intercollegiate Guidelines Network methodology checklist. Literature search resulted in 806 discrete articles. After screening, 11 studies were identified for inclusion in systematic review. Included studies investigated 5 sock, 3 antiperspirant, and 3 barrier strategies. Only 2 articles were determined to have moderate confidence in effect estimate. Clinical and methodologic diversity precluded meta-analysis. Despite the high frequency, discomfort, and associated cost there is a paucity of high-quality quality evidence in support of socks, antiperspirants, or barriers for the prevention of friction blisters. Moderate confidence in effect estimate suggests that paper tape may be an effective form of barrier prevention.
本系统评价的目的是确定袜子、止汗剂或屏障策略在预防荒野和户外徒步活动中摩擦水疱方面是否有效。我们对PubMed和EMBASE进行了检索。由两名作者根据预先确定的纳入和排除标准对标题、摘要和全文文章进行筛选，以识别研究足部摩擦水疱预防方法的前瞻性对照试验。仅考虑与荒野和户外徒步活动（跑步、徒步旅行、行军等）相关的水疱。使用预先设计的表格完成预定数据集的提取。利用苏格兰跨学院指南网络方法检查表确定效应估计的可信度。文献检索共获得806篇独立文章。筛选后，确定11项研究纳入系统评价。纳入的研究调查了5种袜子、3种止汗剂和3种屏障策略。只有2篇文章被确定对效应估计有中等可信度。临床和方法学的多样性使得无法进行荟萃分析。尽管摩擦水疱出现频率高、令人不适且相关成本高，但缺乏高质量证据支持使用袜子、止汗剂或屏障来预防摩擦水疱。对效应估计的中等可信度表明，纸胶带可能是一种有效的屏障预防形式。
