From the Sanford School of Medicine (Ferguson) and the School of Health Sciences (Sudhagoni), University of South Dakota, and Vance Thompson Vision (Swan, Ibach, Schweitzer, Berdahl), Sioux Falls, South Dakota, USA.
From the Sanford School of Medicine (Ferguson) and the School of Health Sciences (Sudhagoni), University of South Dakota, and Vance Thompson Vision (Swan, Ibach, Schweitzer, Berdahl), Sioux Falls, South Dakota, USA.
J Cataract Refract Surg. 2017 May;43(5):622-626. doi: 10.1016/j.jcrs.2017.02.029.
To evaluate the safety and efficacy of a trabecular microbypass stent (iStent) combined with cataract surgery in patients with pseudoexfoliation glaucoma (PXG).
Vance Thompson Vision, Sioux Falls, South Dakota, USA.
Retrospective case series.
Eyes with PXG had implantation of 1 stent. Data were collected preoperatively and postoperatively through 24 months. Data included intraocular pressure (IOP), number of glaucoma medications, the incidence of postoperative IOP pressure spikes of 15 mm Hg or higher at any timepoint, and the need for additional surgery.
The series included 115 eyes. The mean preoperative IOP was 20.00 mm Hg ± 6.95 (SD). One year postoperatively, the mean IOP was 15.54 ± 3.83 mm Hg (P < .01). At 2 years, the mean IOP was 14.51 ± 2.79 (P < .01). The mean number of glaucoma medications was 1.41 ± 1.04 preoperatively and 0.71 ± 0.94 2 years postoperatively (P < .01), indicating a 50% reduction in medication use. Postoperatively, 7 eyes (6%) had an IOP spike of 15 mm Hg or higher above the baseline IOP; the spikes responded to topical therapy. Ninety-eight percent of patients with an IOP of 20 mm Hg or higher achieved a reduction in IOP at the last follow-up.
Trabecular microbypass stent implantation during cataract surgery safely and effectively lowered IOP and medication use in patients with mild to severe PXG.
评估小梁微旁路支架（iStent）联合白内障手术治疗假性剥脱性青光眼（PXG）患者的安全性和疗效。
美国南达科他州苏福尔斯的万斯·汤普森视觉公司。
回顾性病例系列。
对患有 PXG 的眼睛植入 1 个支架。通过 24 个月的术前和术后收集数据。数据包括眼压（IOP）、青光眼药物数量、任何时间点IOP 压力升高 15mmHg 或更高的术后发生率，以及是否需要额外手术。
该系列包括 115 只眼。术前平均眼压为 20.00mm Hg±6.95（SD）。术后 1 年，平均眼压为 15.54±3.83mm Hg（P<.01）。2 年后，平均眼压为 14.51±2.79mm Hg（P<.01）。术前平均青光眼药物数为 1.41±1.04，术后 2 年为 0.71±0.94（P<.01），表明药物使用减少了 50%。术后 7 只眼（6%）眼压升高 15mmHg 或更高，高于基线眼压；眼压升高通过局部治疗得到缓解。98%的眼压为 20mmHg 或更高的患者在最后一次随访时眼压得到降低。
小梁微旁路支架植入术联合白内障手术可安全有效地降低轻度至重度 PXG 患者的眼压和药物使用量。
