Harvey Bryan M, Eussen Simone R B M, Harthoorn Lucien F, Burks A Wesley
*Children's Investigational Research Program, LLC (ChiRP), Bentonville, AR †Nutricia Research, Nutricia Advanced Medical Nutrition, Utrecht, The Netherlands ‡University of North Carolina, School of Medicine, Chapel Hill, NC.
J Pediatr Gastroenterol Nutr. 2017 Sep;65(3):346-349. doi: 10.1097/MPG.0000000000001655.
Data on the mineral status of infants with cow's milk allergy (CMA) consuming an amino acid-based formula (AAF) have not been published. The present study aims to assess mineral status of term infants age 0 to 8 months diagnosed with CMA receiving an AAF for 16 weeks. Serum concentrations of calcium, phosphorus, chloride, sodium, potassium, magnesium, and ferritin were determined in 82 subjects at baseline and in 66 subjects after 16 weeks on AAF using standard methods and evaluated against age-specific reference ranges. In addition to this, individual estimated energy and mineral intakes were compared to Adequate Intakes defined by the European Food Safety Authority and the US Institute of Medicine. The results of this study show that the AAF was effective in providing an adequate mineral status in infants with CMA. The vast majority of infants aged 0 to 6 months (formula only) and aged 6 to 12 months (formula and complementary foods) had adequate mineral intakes.
关于食用氨基酸配方奶粉（AAF）的牛奶过敏（CMA）婴儿矿物质状况的数据尚未公布。本研究旨在评估0至8个月大的足月CMA婴儿在接受AAF治疗16周后的矿物质状况。使用标准方法在82名受试者基线时以及66名受试者在接受AAF治疗16周后测定血清钙、磷、氯、钠、钾、镁和铁蛋白浓度，并根据特定年龄参考范围进行评估。除此之外，还将个体估计能量和矿物质摄入量与欧洲食品安全局和美国医学研究所定义的适宜摄入量进行了比较。本研究结果表明，AAF能有效为CMA婴儿提供充足的矿物质状况。绝大多数0至6个月（仅食用配方奶粉）和6至12个月（食用配方奶粉和辅食）的婴儿矿物质摄入量充足。
