CCNU-uOttawa Joint Research Centre, Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, Hubei 430079, China.
Chem Soc Rev. 2017 Jul 17;46(14):4135-4149. doi: 10.1039/c6cs00276e.
Great achievements in the asymmetric cyclization reactions of sulfur ylides have been reached by using chiral sulfides; however, this method usually suffers from the high loading of chiral sulfides. Over the past decade, new catalysis technologies beyond chiral sulfide-based catalysis have been gradually applied to the cyclizations of sulfur ylides. These technologies, including organocatalysis, organometallic catalysis and photocatalysis, can avoid the use of stoichiometric chiral pools and enable the development of new cyclization reactions of sulfur ylides. In this tutorial review, recent advances in this rapidly developing field will be highlighted with particular emphases on the catalytic mechanism and the development of new reactions, new reagents and new concepts.
手性硫化物在不对称环化反应中取得了巨大的成就；然而，该方法通常需要高负载量的手性硫化物。在过去的十年中，超越手性硫化物催化的新催化技术逐渐应用于硫叶立德的环化反应。这些技术包括有机催化、有机金属催化和光催化，可以避免使用化学计量的手性库，并能够开发新的硫叶立德环化反应。在这篇综述中，将重点介绍该快速发展领域的最新进展，特别强调催化机制以及新反应、新试剂和新概念的发展。
