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2012年印度西孟加拉邦农村地区的登革热:一次疫情调查

Dengue fever in a rural area of West Bengal, India, 2012: an outbreak investigation.

作者信息

Biswas Dilip K, Bhunia Rama, Basu Mausumi

机构信息

Deputy Chief Medical Officer of Health-II, district Purba Medinipur, West Bengal, India.

Lady Duffrin Victoria Hospital, Kolkata, West Bengal, India.

出版信息

WHO South East Asia J Public Health. 2014 Jan-Mar;3(1):46-50. doi: 10.4103/2224-3151.206883.

DOI:10.4103/2224-3151.206883
PMID:28607254
Abstract

BACKGROUND

During September 2012, an increased number of fever cases was reported from Ramnagar-II block, Purba Medinipur district. This study investigated the outbreak, with the following objectives: to describe the distribution of fever cases, to determine the risk factors and to recommend preventive measures.

MATERIALS AND METHODS

The clinical features, date of onset and outcome of all cases of fever were listed. Blood specimens were collected from affected patients and sent for serological examination. An epidemic curve was plotted and environmental and entomological surveys were carried out.

RESULTS

There was a total of 100 cases, of which 56% (56/100) were men.Among the four villages studied, the highest number of cases was from Gopalpur 37% (37/100), followed by Badalpur 26% (26/100); 19% (19/100) of cases had a history of migration from dengue-endemic areas. The majority of cases were in age group 15-45 years - 52% (52/100), followed by the age group >45 years - 28% (28/100). All the cases had history of fever (100%), followed by myalgia - 82%, headache - 78%, and retro-orbital pain - 73%. The outbreak started on 7 September 2012, peaked on 18 September, then gradually declined and no further cases were noted after 28 September 2012. Seventy-nine percent (79/100) of cases were NS1 test positive (non-structural antigen-1) and 72% (13/18) cases were positive on a dengue monoclonal antibody (IgM) capture enzyme-linked immunosorbent assay (MAC-ELISA) test. All recovered except one (case-fatality ratio: 1%). The values for Household Index, Container lndex and Breteau Index of the four villages were: Badalpur, 3%, 10% and 5%; Gopalpur, 13%, 23% and 18%; Ramchandrapur, 9%, 11%, and 13%; and Tajpur, 2%, 2% and 2%.

CONCLUSION

The outbreak was probably due to dengue fever. The study led to a recommendation to destroy water containers and use mosquito nets. The outbreak was controlled.

摘要

背景

2012年9月期间,西孟加拉邦普尔巴梅迪尼布尔县拉姆纳加尔二区报告的发热病例数量有所增加。本研究对此次疫情进行了调查,目标如下:描述发热病例的分布情况,确定风险因素并推荐预防措施。

材料与方法

列出所有发热病例的临床特征、发病日期及转归情况。采集受影响患者的血液样本并送去进行血清学检查。绘制了流行曲线,并开展了环境和昆虫学调查。

结果

共有100例病例,其中56%(56/100)为男性。在所研究的四个村庄中,病例数最多的是戈帕尔布尔村,占37%(37/100);其次是巴达尔布尔村,占26%(26/100);19%(19/100)的病例有从登革热流行地区迁移的病史。大多数病例年龄在15至45岁之间,占病例总数的52%(52/100);其次是年龄大于45岁的病例,占28%(28/100)。所有病例均有发热史(100%),其次是肌痛——82%,头痛——78%,以及眼眶后疼痛——73%。疫情于2012年9月7日开始,9月18日达到高峰,随后逐渐下降,2012年9月28日之后未再出现新病例。79%(79/100)的病例NS1检测呈阳性(非结构抗原1),72%(13/18)的病例在登革热单克隆抗体(IgM)捕获酶联免疫吸附测定(MAC-ELISA)检测中呈阳性。除1例死亡外,其余均康复(病死率:1%)。四个村庄的家庭指数、容器指数和布雷托指数值分别为:巴达尔布尔村,3%、10%和5%;戈帕尔布尔村,13%、23%和18%;拉姆钱德拉布尔村,9%、11%和13%;以及塔杰布尔村,2%、2%和2%。

结论

此次疫情可能是由登革热引起的。该研究建议销毁储水容器并使用蚊帐。疫情得到了控制。

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