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经皮球囊椎体后凸成形术治疗症状性许莫氏结节的回顾性研究:5年结果

A Retrospective Study of Percutaneous Balloon Kyphoplasty for the Treatment of Symptomatic Schmorl's Nodes: 5-Year Results.

作者信息

Zhi-Yong Sun, Huan Zhao, Feng Ling, Nan-Ning Lv, Xiao-Yu Zhu, Bin Pi, Jun Lin, Zhong-Lai Qian, Zhi-Ming Zhang, Hui-Lin Yang

机构信息

Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China (mainland).

Department of Orthopaedic Surgery, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China (mainland).

出版信息

Med Sci Monit. 2017 Jun 13;23:2879-2889. doi: 10.12659/msm.904802.

Abstract

BACKGROUND Despite literature supporting the efficiency of percutaneous balloon kyphoplasty (PKP) in treating osteoporotic and malignant vertebral compression fractures, few reports exist that document its use for treatment of symptomatic Schmorl's nodes (SNs) refractory to conservative treatment. Patients with symptomatic SNs could have pain in the vertebrae similar to an acute vertebral compression fracture. MRI is very helpful in diagnosing symptomatic SNs when x-ray and CT scan are unremarkable. In painful cases, the vertebrae bone marrow around the SNs is hyperintense on T2-weighted subsequence. We evaluated the long-term safety and effectiveness of PKP for the treatment of symptomatic SNs not responding to conservative therapy. MATERIAL AND METHODS From January 2008 to December 2012, 32 patients suffering from symptomatic SNs underwent 43 PKP procedures. Outcome data, including mean height ratio of anterior and middle vertebral body, Visual Analog Scale (VAS score) for pain measurement, Oswestry Disability Indexes (ODI score) and SF-36 questionnaires for function measurement were recorded preoperatively, postoperatively, and at one month, six months, two years, and five years after treatment. RESULTS Thirty-two patients were treated successfully with PKP. Clinically asymptomatic cement leakage was observed in three (6.98%) of the treated vertebral bodies. The mean height ratio of anterior and middle vertebral bodies changed from 98.2±1.6% preoperatively to 98.5±1.4% postoperatively (p>0.05) and 98.3±1.5% preoperatively to 98.8±1.9% postoperatively (p>0.05). The mean VAS scores, ODI score, and SF-36 scores for physical function (PF), bodily pain (BF), social functioning (SF), and vitality (VT) all showed significant improvements (p<0.05). During the 5-year follow-up, the stabilization of the height of the vertebral body and functional improvements were all maintained. CONCLUSIONS PKP is a safe and effective procedure for the treatment of symptomatic SNs refractory to conservative therapy.

摘要

背景 尽管有文献支持经皮球囊后凸成形术(PKP)治疗骨质疏松性和恶性椎体压缩骨折的有效性,但很少有报告记录其用于治疗经保守治疗无效的有症状许莫氏结节(SNs)。有症状的SNs患者可能会出现与急性椎体压缩骨折相似的椎体疼痛。当X线和CT扫描无明显异常时,MRI对诊断有症状的SNs非常有帮助。在疼痛病例中,SNs周围的椎体骨髓在T2加权序列上呈高信号。我们评估了PKP治疗经保守治疗无效的有症状SNs的长期安全性和有效性。

材料与方法 2008年1月至2012年12月,32例有症状的SNs患者接受了43次PKP手术。记录术前、术后以及治疗后1个月、6个月、2年和5年的结果数据,包括椎体前、中高度比值、用于疼痛测量的视觉模拟量表(VAS评分)、用于功能测量的Oswestry功能障碍指数(ODI评分)和SF-36问卷。

结果 32例患者接受PKP治疗成功。在3个(6.98%)治疗椎体中观察到临床无症状的骨水泥渗漏。椎体前、中高度比值术前为98.2±1.6%,术后为98.5±1.4%(p>0.05),术前为98.3±1.5%,术后为98.8±1.9%(p>0.05)。平均VAS评分、ODI评分以及SF-36身体功能(PF)、身体疼痛(BF)、社会功能(SF)和活力(VT)评分均有显著改善(p<0.05)。在5年随访期间,椎体高度的稳定和功能改善均得以维持。

结论 PKP是治疗经保守治疗无效的有症状SNs的一种安全有效的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a08/5478245/6f967ff2c374/medscimonit-23-2879-g001.jpg

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