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经皮椎体成形术治疗症状性许莫氏结节:11例长期随访及文献复习

Percutaneous Vertebroplasty for Symptomatic Schmorl's Nodes: 11 Cases with Long-term Follow-up and a Literature Review.

作者信息

He Shi-Cheng, Zhong Bin-Yan, Zhu Hai-Dong, Fang Wen, Chen Li, Guo Jin-He, Deng Gang, Teng Gao-Jun

机构信息

Department of Radiology, Zhong-da Hospital, Medical School, Southeast University, Nanjing 210009, China.

出版信息

Pain Physician. 2017 Feb;20(2):69-76.

Abstract

BACKGROUND

Percutaneous vertebroplasty (PVP) is commonly used to treat symptomatic vertebral compression fractures. However, its long-term effectiveness and safety for use in the treatment of symptomatic Schmorl's nodes (SNs) refractory to conservative treatment is uncertain.

OBJECTIVES

To present a case series with PVP for symptomatic SNs not responding to conservative therapy and assess the effectiveness and safety for such treatment with long-term follow-up. To present a review of the literature regarding SNs and treatment options.

STUDY DESIGN

Single center retrospective observational study.

SETTING

This study consists of patients from a large academic center in China.

METHODS

Between January 2008 and December 2013, 11 patients suffering from symptomatic SNs that were refractory to medical or physical therapy, underwent PVP procedures in our department. All patients had a definitive diagnosis of SNs by magnetic resonance imaging (MRI) and computed tomography (CT). The visual analog scale (VAS) was assessed preoperatively at 4 hours, at one month, and every 6 months postoperatively during the long-term (mean: 58.0 months) follow-up period.

RESULTS

Each of the 11 patients reported an immediate and distinct relief of their back pain. No one reported a worsening of symptoms. The VAS decreased from an average preprocedural score of 7.9 to a postprocedural score of 2.1 at 4 hours. The VAS averaged 1.8 during the mean follow-up period of 58.0 (range 24.1 to 98.9) months. There were no postoperative complications during the follow-up period. At the end of the follow-up period, all 11 patients were unrestricted in their activities.

LIMITATIONS

This study is a retrospective study with a small sample size.

CONCLUSIONS

PVP is an effective and safe procedure for the treatment of symptomatic SNs, which are refractory to medical or physical therapy.Key words: Percutaneous vertebroplasty, symptomatic Schmorl's nodes, vertebral endplate fracture, endplate osteonecrosis, Modic changes.

摘要

背景

经皮椎体成形术(PVP)常用于治疗有症状的椎体压缩骨折。然而,其用于治疗经保守治疗无效的有症状许莫氏结节(SNs)的长期有效性和安全性尚不确定。

目的

呈现一组采用PVP治疗对保守治疗无反应的有症状SNs的病例系列,并通过长期随访评估该治疗方法的有效性和安全性。对有关SNs及治疗选择的文献进行综述。

研究设计

单中心回顾性观察研究。

研究地点

本研究纳入了来自中国一家大型学术中心的患者。

方法

2008年1月至2013年12月期间,11例经药物或物理治疗无效的有症状SNs患者在我科接受了PVP手术。所有患者均通过磁共振成像(MRI)和计算机断层扫描(CT)明确诊断为SNs。在长期(平均58.0个月)随访期间,术前4小时、术后1个月以及术后每6个月评估视觉模拟量表(VAS)。

结果

11例患者均报告背痛立即且明显缓解。无人报告症状恶化。VAS评分在术前平均为7.9分,术后4小时降至2.1分。在平均58.0(范围24.1至98.9)个月的随访期间,VAS平均为1.8分。随访期间无术后并发症。随访期末,所有11例患者活动均不受限。

局限性

本研究为回顾性研究,样本量小。

结论

PVP是治疗经药物或物理治疗无效的有症状SNs的一种有效且安全的方法。关键词:经皮椎体成形术,有症状许莫氏结节,椎体终板骨折,终板骨坏死,Modic改变

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