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一项团体提供的自我管理计划可减轻多发性硬化症患者的痉挛:一项随机对照试验。

A group-delivered self-management program reduces spasticity in people with multiple sclerosis: A randomized, controlled pilot trial.

作者信息

Hugos Cinda L, Bourdette Dennis, Chen Yiyi, Chen Zunqiu, Cameron Michelle

机构信息

VA Portland Health Care System (HCS), USA Oregon Health & Science University, USA.

Oregon Health & Science University, USA.

出版信息

Mult Scler J Exp Transl Clin. 2017 Mar 23;3(1):2055217317699993. doi: 10.1177/2055217317699993. eCollection 2017 Jan-Mar.

Abstract

BACKGROUND

Spasticity affects more than 80% of people with multiple sclerosis (MS), affecting activity, participation, and quality of life. Based on an international guideline, an MS spasticity group education and stretching program, MS Spasticity: Take Control (STC), has been developed.

OBJECTIVE

The objective of this paper is to determine whether STC with home stretching is associated with greater changes in spasticity than usual care (UC), consisting of an illustrated stretching booklet and home stretching but without group instruction or support, in people with MS.

METHODS

Ambulatory MS patients with self-reported spasticity interfering with daily activities were randomized to STC or UC. Individuals completed questionnaires regarding MS, spasticity, walking, fatigue and mood, and physical measures of spasticity and walking.

RESULTS

Thirty-eight of 40 participants completed both assessments. Mean total score and scores on two subscales of the MS Spasticity Scale-88 improved more with STC than with UC ( < 0.03). There was no significant change in the Modified Ashworth Scale in either group. Mean scores on the Modified Fatigue Impact Scale, the Beck Depression Inventory-II, and the physical component of the Multiple Sclerosis Impact Scale-29 showed statistically and clinically significant improvements in the STC group only.

CONCLUSIONS

Participation in STC improved self-reported impact of spasticity more than UC and provided encouraging improvements in other measures.

摘要

背景

痉挛影响超过80%的多发性硬化症(MS)患者,对其活动、参与度和生活质量产生影响。基于一项国际指南,已制定了一项MS痉挛小组教育和伸展计划,即“MS痉挛:掌控局面(STC)”。

目的

本文的目的是确定在MS患者中,接受家庭伸展训练的STC计划与常规护理(UC)相比,在痉挛方面是否有更大的变化,常规护理包括一本带插图的伸展手册和家庭伸展训练,但没有小组指导或支持。

方法

自我报告痉挛干扰日常活动的非卧床MS患者被随机分为STC组或UC组。个体完成了关于MS、痉挛、行走、疲劳和情绪的问卷调查,以及痉挛和行走的身体测量。

结果

40名参与者中有38名完成了两项评估。MS痉挛量表-88的平均总分和两个子量表的得分,STC组比UC组改善得更多(<0.03)。两组改良Ashworth量表均无显著变化。改良疲劳影响量表、贝克抑郁量表-II和多发性硬化症影响量表-29的身体成分平均得分仅在STC组有统计学和临床意义上的显著改善。

结论

参与STC计划比UC组更能改善自我报告的痉挛影响,并在其他指标上有令人鼓舞的改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/829b/5433226/a3a768191f2c/10.1177_2055217317699993-fig1.jpg

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