Phenobarbital increases spontaneous transmitter release at the frog neuromuscular junction.
作者信息
Pincus J H, Insler N F
出版信息
Yale J Biol Med. 1978 Mar-Apr;51(2):185-9.
Abstract
Phenobarbital (1-2 × 10(-4)M) markedly increases the frequency of miniature end-plate potentials at the neuromuscular synapse of the frog. This effect was seen in calcium free media containing EGTA. The drug probably acts presynaptically at an intracellular locus to increase the presynaptic free calcium concentration.
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