Misra Paraish S, Nessim Sharon J
Division of Nephrology, University of Toronto, Toronto, ON, Canada.
Division of Nephrology, Jewish General Hospital, McGill University, Montreal, QC, Canada.
Semin Dial. 2017 Sep;30(5):438-445. doi: 10.1111/sdi.12613. Epub 2017 Jun 13.
Magnesium balance is infrequently discussed in the dialysis population, and the clinical consequences of derangements in magnesium homeostasis are incompletely understood. There is an association between hypomagnesemia and adverse outcomes including increases in cardiovascular disease and mortality, while elevated magnesium levels have also been linked with complications such as osteomalacia. In this review, we discuss the features of magnesium physiology relevant to dialysis patients and provide an updated summary of the literature linking magnesium derangements with bone disease, cardiovascular disease, sudden cardiac death, and mortality.
镁平衡在透析人群中很少被讨论，镁稳态紊乱的临床后果也未被完全理解。低镁血症与不良后果有关，包括心血管疾病增加和死亡率上升，而镁水平升高也与诸如骨软化症等并发症有关。在这篇综述中，我们讨论了与透析患者相关的镁生理学特征，并提供了将镁紊乱与骨病、心血管疾病、心源性猝死和死亡率联系起来的文献的最新总结。
