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一名小细胞肺癌患者的上腔静脉综合征:病例报告

Superior Vena Cava Syndrome in a Patient with Small-Cell Lung Cancer: A Case Report.

作者信息

Brzezniak Christina, Oronsky Bryan, Carter Corey A, Thilagar Bennett, Caroen Scott, Zeman Karen

机构信息

aWalter Reed Military Medical Center Bethesda, Bethesda, Maryland, USA.

bEpicentRx, San Diego, California, USA.

出版信息

Case Rep Oncol. 2017 Mar 17;10(1):252-257. doi: 10.1159/000464278. eCollection 2017 Jan-Apr.

DOI:10.1159/000464278
PMID:28611639
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5465747/
Abstract

Superior vena cava (SVC) syndrome, a potential oncologic emergency, is closely associated with malignancy and right-sided lung cancer in particular. A case of SVC syndrome presenting with facial swelling, neck distension, and enlarged veins of the upper chest, which developed over a period of 5 weeks in a 46-year-old patient on a clinical trial with small-cell lung cancer, is reported. Computed tomography scan of the chest revealed slight enlargement of a superior conglomerate mediastinal lymphadenopathy and intramural thrombus of the SVC. The etiology, diagnosis, and treatment of the SVC syndrome are discussed.

摘要

上腔静脉(SVC)综合征是一种潜在的肿瘤急症,与恶性肿瘤密切相关,尤其是右侧肺癌。本文报告了一例SVC综合征病例,该患者为一名46岁的小细胞肺癌临床试验患者,在5周内出现面部肿胀、颈部肿胀和上胸部静脉扩张。胸部计算机断层扫描显示上纵隔淋巴结肿大轻微,SVC壁内血栓形成。文中讨论了SVC综合征的病因、诊断和治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d550/5465747/a6d9760f96ea/cro-0010-0252-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d550/5465747/eee24ea1d347/cro-0010-0252-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d550/5465747/d76d2f6c31ae/cro-0010-0252-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d550/5465747/986c12a604f3/cro-0010-0252-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d550/5465747/b298f1487fea/cro-0010-0252-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d550/5465747/a6d9760f96ea/cro-0010-0252-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d550/5465747/eee24ea1d347/cro-0010-0252-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d550/5465747/d76d2f6c31ae/cro-0010-0252-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d550/5465747/986c12a604f3/cro-0010-0252-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d550/5465747/b298f1487fea/cro-0010-0252-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d550/5465747/a6d9760f96ea/cro-0010-0252-g05.jpg

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本文引用的文献

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Comprehensive Imaging Review of the Superior Vena Cava.上腔静脉的综合影像学评估
Radiographics. 2015 Nov-Dec;35(7):1873-92. doi: 10.1148/rg.2015150056. Epub 2015 Oct 9.
2
Surgical management of superior vena cava syndrome following pacemaker lead infection: a case report and review of the literature.起搏器导线感染后上腔静脉综合征的外科治疗:一例报告并文献复习
J Cardiothorac Surg. 2014 Jun 19;9:107. doi: 10.1186/1749-8090-9-107.
3
Superior vena cava syndrome: A medical emergency?上腔静脉综合征:一种医疗急症?
患有呼吸窘迫、面部水肿和难治性低钾血症的患者。
BMJ Case Rep. 2021 May 7;14(5):e240330. doi: 10.1136/bcr-2020-240330.
4
Signet-ring cell adenocarcinoma of unknown primary presenting with superior vena cava (SVC) syndrome: rare type of cancer.以腔静脉综合征为表现的原发灶不明的印戒细胞腺癌:罕见的癌症类型。
BMJ Case Rep. 2019 Dec 29;12(12):e232269. doi: 10.1136/bcr-2019-232269.
Int J Angiol. 2008 Spring;17(1):43-6. doi: 10.1055/s-0031-1278280.
4
Superior vena cava syndrome--a proposed classification system and algorithm for management.上腔静脉综合征——一种拟议的分类系统及管理算法
J Thorac Oncol. 2008 Aug;3(8):811-4. doi: 10.1097/JTO.0b013e3181804791.
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Superior vena cava syndrome: 1757-2007.上腔静脉综合征:1757年至2007年。
Hellenic J Cardiol. 2007 Nov-Dec;48(6):366-7.
6
Clinical practice. Superior vena cava syndrome with malignant causes.临床实践。恶性病因导致的上腔静脉综合征。
N Engl J Med. 2007 May 3;356(18):1862-9. doi: 10.1056/NEJMcp067190.
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