De Crea Carmela, Raffaelli Marco, Sessa Luca, Lombardi Celestino Pio, Bellantone Rocco
Istituto di Semeiotica Chirurgica, U.O. Chirurgia Endocrina e Metabolica, Università Cattolica del Sacro Cuore, Policlinico A. Gemelli, L.go A. Gemelli 8, 00168, Rome, Italy.
Updates Surg. 2017 Jun;69(2):205-209. doi: 10.1007/s13304-017-0468-2. Epub 2017 Jun 13.
One of the most controversial issues in the treatment of thyroid cancer is the management of the central neck nodes in patients with papillary thyroid carcinoma (PTC). Lymph node involvement is common in patients with PTC and it may negatively affect recurrence rate and, probably, survival. Although therapeutic compartment-oriented central neck dissection is the standard treatment for patients with clinical nodal involvement (cN1) PTC, the role and the extension for elective or prophylactic central neck dissection (PCND) in patients with clinically node negative (cN0) neoplasms remains controversial. In recent years, in order to decrease the risk of postoperative complications related to PCND, unilateral central neck dissection has emerged as an alternative approach to bilateral central neck dissection.
甲状腺癌治疗中最具争议的问题之一是甲状腺乳头状癌(PTC)患者中央区颈部淋巴结的处理。PTC患者中淋巴结受累很常见,这可能会对复发率产生负面影响,甚至可能影响生存率。尽管针对有临床淋巴结受累(cN1)的PTC患者,以治疗分区为导向的中央区颈部清扫术是标准治疗方法,但对于临床淋巴结阴性(cN0)肿瘤患者,选择性或预防性中央区颈部清扫术(PCND)的作用和范围仍存在争议。近年来,为了降低与PCND相关的术后并发症风险,单侧中央区颈部清扫术已成为双侧中央区颈部清扫术的替代方法。