Woodcock Mark E, Idoko-Akoh Alewo, McGrew Michael J
The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Easter Bush Campus, Midlothian, EH25 9RG, UK.
Mamm Genome. 2017 Aug;28(7-8):315-323. doi: 10.1007/s00335-017-9701-z. Epub 2017 Jun 13.
The application of gene editing (GE) technology to create precise changes to the genome of bird species will provide new and exciting opportunities for the biomedical, agricultural and biotechnology industries, as well as providing new approaches for producing research models. Recent advances in modifying both the somatic and germ cell lineages in chicken indicate that this species, and conceivably soon other avian species, has joined a growing number of model organisms in the gene editing revolution.
基因编辑(GE)技术应用于对鸟类基因组进行精确改造,将为生物医学、农业和生物技术产业带来全新且令人兴奋的机遇,同时也为生产研究模型提供新方法。近期在鸡的体细胞和生殖细胞系改造方面取得的进展表明,该物种以及可能很快其他鸟类物种,已在基因编辑革命中加入了越来越多的模式生物行列。