Burton-Freeman Britt M, Sandhu Amandeep K, Edirisinghe Indika
Center for Nutrition Research, Institute for Food Safety and Health, Illinois Institute of Technology, IL, USA.
Food Funct. 2017 Sep 20;8(9):3010-3032. doi: 10.1039/c7fo00190h.
The diet is an essential factor affecting the risk for development and progression of modern day chronic diseases, particularly those with pathophysiological roots in inflammation and oxidative stress-induced damage. The potential impact of certain foods and their bioactive compounds to reverse or prevent destructive dysregulated processes leading to disease has attracted intense research attention. The mango (Mangifera indica Linn.) is a tropical fruit with distinctive nutritional and phytochemical composition. Notably, the mango contains several essential water- and lipid-soluble micronutrients along with the distinguishing phytochemicals gallotannins and mangiferin. In vitro and in vivo studies reveal various mechanisms through which mangos or their associated compounds reduce risk or reverse metabolic- and inflammation-associated diseases. Health benefits of isolated individual mango compounds and extracts from mango by-products are well described in the literature with less attention devoted to the whole fruit. Here, we review and summarize the available literature assessing the health promoting potential of mango flesh, the edible portion contributing to dietary fruit intake, focusing specifically on modern day health issues of obesity and the risk factors and diseases it precipitates, including diabetes and cardiovascular disease. Additionally, this review explores new insights on the benefits of mango for brain, skin and intestinal health. Overall, the foundation of research supporting the potential role of mangos in reducing risk for inflammation- and metabolically-based chronic diseases is growing.
饮食是影响现代慢性病发生和发展风险的一个重要因素，尤其是那些病理生理根源在于炎症和氧化应激诱导损伤的疾病。某些食物及其生物活性化合物对逆转或预防导致疾病的破坏性失调过程的潜在影响已引起了广泛的研究关注。芒果（Mangifera indica Linn.）是一种具有独特营养和植物化学成分的热带水果。值得注意的是，芒果含有几种必需的水溶性和脂溶性微量营养素以及独特的植物化学物质没食子单宁和芒果苷。体外和体内研究揭示了芒果或其相关化合物降低风险或逆转代谢和炎症相关疾病的各种机制。文献中对分离出的单个芒果化合物和芒果副产品提取物的健康益处有详细描述，但对整个果实的关注较少。在这里，我们回顾并总结了现有文献，评估了芒果果肉（即构成膳食水果摄入量的可食用部分）促进健康的潜力，特别关注肥胖这一现代健康问题及其引发的风险因素和疾病，包括糖尿病和心血管疾病。此外，本综述探讨了芒果对大脑、皮肤和肠道健康益处的新见解。总体而言，支持芒果在降低炎症和代谢性慢性病风险中潜在作用的研究基础正在不断扩大。
