Tadesse Tsegay Zenebe, Smaoui Slim, Varzakas Theodoros
Department of Food Science and Post-Harvest Technology, College of Dryland Agriculture and Natural Resources, Mekelle University, P.O. Box 231, Mekelle, Ethiopia.
Laboratory of Microbial and Enzymatic Biotechnologies and Biomolecules, Center of Biotechnology of Sfax (CBS), University of Sfax, Road of Sidi Mansour Km 6, P.O. Box 1177, Sfax, 3018, Tunisia.
Open Life Sci. 2025 May 21;20(1):20251105. doi: 10.1515/biol-2025-1105. eCollection 2025.
The abundant and renewable resources from fruit by-products are getting emphasis on their valorization. These by-products may contain toxic substances due to factors such as cultivation, harvesting, transportation, preservation, or processing. Hence, presenting scientific overviews of the toxicological qualities and detoxification trends of these by-products are critical for implicating their possible valorization. The present demand for valorization of fruit by-products requires emphasis and methodologies for the detoxification of any toxicants to develop healthier products. This review emphasized the toxicological qualities of by-products from fruits for which the maximum global production occurred in 2022. In this review, heavy metals (arsenic, cadmium, cobalt, chromium, nickel, lead, and mercury), mycotoxins, toxicant organic compounds, anti-nutritional factors, and pesticide/fungicide residues of the selected fruit byproducts were discussed. Current trends to reduce possible toxicants of these by-products during their valorization were emphasized. Novel functional foods valorized from these fruit by-products and future perspectives of detoxification were also focused on in this review.
水果副产品丰富且可再生的资源正因其价值提升而受到重视。由于种植、收获、运输、保存或加工等因素，这些副产品可能含有有毒物质。因此，对这些副产品的毒理学特性和解毒趋势进行科学概述对于实现其可能的价值提升至关重要。目前对水果副产品价值提升的需求要求重视对任何有毒物质进行解毒的方法，以开发更健康的产品。本综述强调了2022年全球产量最高的水果副产品的毒理学特性。在本综述中，讨论了所选水果副产品中的重金属（砷、镉、钴、铬、镍、铅和汞）、霉菌毒素、有毒有机化合物、抗营养因子以及农药/杀菌剂残留。强调了在这些副产品价值提升过程中减少其可能有毒物质的当前趋势。本综述还关注了由这些水果副产品制成的新型功能食品以及解毒的未来前景。
