背板在波士顿I型人工角膜角度解剖学中的作用。

The Role of the Back Plate in Angle Anatomy with the Boston Type I Keratoprosthesis.

作者信息

Taniguchi Elise V, Paschalis Eleftherios I, Crnej Alja, Ren Ai, Colby Kathryn A, Chodosh James, Pasquale Louis R, Shen Lucy Q, Dohlman Claes H, Cruzat Andrea

机构信息

*Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA; †Department of Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil; ‡Department of Ophthalmology, University of Chicago Medical Center, Chicago, IL; and §Department of Ophthalmology, Pontificia Universidad Católica de Chile, Santiago, Chile.

出版信息

Cornea. 2017 Sep;36(9):1096-1101. doi: 10.1097/ICO.0000000000001248.

DOI:10.1097/ICO.0000000000001248

PMID:28614155

Abstract

PURPOSE

To quantitatively evaluate the angle anatomy in eyes with the Boston type I keratoprosthesis (B-KPro) differing in the back plate (BP) material and size using anterior segment optical coherence tomography.

METHODS

B-KPro eyes with poly(methyl methacrylate) (PMMA) (7.0 and 8.5 mm) and titanium (7.0, 8.5, and 9.5 mm) BPs were imaged with anterior segment optical coherence tomography. The angle opening distance at 500 μm from the scleral spur (AOD500), trabecular iris surface area at 500 μm from the scleral spur (TISA500), and trabecular iris angle at 500 μm from the scleral spur (TIA500) were measured. Among the visible quadrants, the average, the temporal, the widest, and the narrowest angle of each eye were included in the analysis. Average time between B-KPro implantation and imaging was 7.5 ± 1.4 years for a PMMA BP and 2.4 ± 2.3 years for a titanium BP (P < 0.0001).

RESULTS

We analyzed 17 B-KPro eyes with PMMA BPs and 24 B-KPro eyes with titanium BPs. The average AOD500 (394.1 ± 226.9 vs. 454.5 ± 255.6 μm, P = 0.44), average TIA500 (26.2 ± 14.2 vs. 29.8 ± 13.9 degrees, P = 0.43), and average TISA500 (0.15 ± 0.08 vs. 0.17 ± 0.10 μm, P = 0.52) were not statistically different between eyes with PMMA and titanium BPs, nor were the temporal, the narrowest, and the widest angle measurements of each eye (all P > 0.05). Similarly, no significant differences were found between the angle measurements of B-KPro eyes with a titanium BP diameter of 8.5 or 9.5 mm (all P > 0.05).

CONCLUSIONS

We successfully visualized the angle anatomy in 66.1% of the imaged eyes, including all BPs studied. Neither the material nor the size of the B-KPro BP had a significant impact on the angle anatomy.

摘要

目的

使用眼前节光学相干断层扫描技术，定量评估采用不同背板（BP）材料和尺寸的波士顿I型人工角膜（B-KPro）植入眼的房角解剖结构。

方法

对采用聚甲基丙烯酸甲酯（PMMA）（7.0和8.5毫米）和钛（7.0、8.5和9.5毫米）背板的B-KPro植入眼进行眼前节光学相干断层扫描成像。测量距巩膜突500微米处的房角开放距离（AOD500）、距巩膜突500微米处的小梁虹膜表面积（TISA500）以及距巩膜突500微米处的小梁虹膜角（TIA500）。在可见象限中，分析每只眼的平均值、颞侧值、最宽值和最窄值。对于PMMA背板，B-KPro植入与成像之间的平均时间为7.5±1.4年，对于钛背板则为2.4±2.3年（P<0.0001）。

结果

我们分析了17只采用PMMA背板的B-KPro植入眼和24只采用钛背板的B-KPro植入眼。采用PMMA背板和钛背板的眼之间，平均AOD500（394.1±226.9对454.5±255.6微米；P=0.44）、平均TIA500（26.2±14.2对29.8±13.9度；P=0.43）和平均TISA500（0.15±0.08对0.17±0.10微米；P=0.52）无统计学差异，每只眼的颞侧、最窄和最宽房角测量值也无统计学差异（均P>0.05）。同样，钛背板直径为8.5或9.5毫米的B-KPro植入眼的房角测量值之间也未发现显著差异（均P>0.05）。