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[印古什共和国多发性硬化症患病率及危险因素分析]

[An analysis of the prevalence and risk factors of multiple sclerosis in the Republic of Ingushetia].

作者信息

Goncharova Z A, Uzhakhov R M

机构信息

Rostov State Medical University, Rostov-on-Don, Russia.

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2017;117(2. Vyp. 2):6-9. doi: 10.17116/jnevro2017117226-9.

Abstract

AIM

To determine epidemiological characteristics and factors related to the development of multiple sclerosis (MS) in the population of the Republic of Ingushetia in 2013-2016.

MATERIAL AND METHODS

A study was carried out in several clinical settings of the Republic of Ingushetia. A special medical form developed for the study was completed by patients. Medical examination of patients was performed as well. Statistical methods were used for data analysis.

RESULTS AND CONCLUSION

A significant variation of MS prevalence was seen. The mean prevalence rate was low - 13.2 cases of MS per 100 000 of population. It was different in ethnic groups: 13.7 per 100 000 of population in Ingush, 15.2 in Chechen and 45 in the Slavonic population. The incidence of MS was 1.76 per 100 000 population in 2015. Different risk factors of MS, including adverse ecological factors and environmental risk predictors (contact with poisons), and their greater role compared to genetic factors were identified.

摘要

目的

确定2013 - 2016年印古什共和国人群中多发性硬化症(MS)的流行病学特征及发病相关因素。

材料与方法

在印古什共和国的多个临床机构开展了一项研究。患者填写了为该研究设计的特殊医学表格。同时对患者进行了医学检查。采用统计方法进行数据分析。

结果与结论

MS患病率存在显著差异。平均患病率较低——每10万人口中有13.2例MS。不同种族群体的患病率有所不同:印古什族每10万人口中有13.7例,车臣族有15.2例,斯拉夫族有45例。2015年MS发病率为每10万人口1.76例。确定了MS的不同风险因素,包括不利的生态因素和环境风险预测因素(接触毒物),且发现这些因素比遗传因素发挥着更大的作用。

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