非常规审讯揭示 HIV 的逃逸计划。

Unconventional Interrogation Yields HIV's Escape Plan.

机构信息

Department of Microbiology, Boston University School of Medicine, Boston, MA 02118, USA.

出版信息

Cell Host Microbe. 2017 Jun 14;21(6):659-660. doi: 10.1016/j.chom.2017.06.003.

DOI:10.1016/j.chom.2017.06.003

Abstract

Chasing HIV-1 across the genotype landscape, unequipped to anticipate its maneuvers, the antibody variable-region genes pursue the virus in futility. In this issue of Cell Host & Microbe, Dingens et al. (2017) exhibit a powerful technology that reveals the escape pathways of HIV-1 and may enable its capture.

摘要

在基因型的世界中追踪 HIV-1，抗体可变区基因没有能力预测病毒的动作，只能徒劳地追寻病毒。在本期《细胞宿主与微生物》中，Dingens 等人（2017）展示了一种强大的技术，揭示了 HIV-1 的逃逸途径，并可能使其被捕获。