Department of Physical Medicine and Rehabilitation, Bağcılar Training and Research Hospital, İstanbul, Turkey.
Department of Orthopedics and Traumatology, Bağcılar Training and Research Hospital, İstanbul, Turkey.
Turk J Med Sci. 2017 Jun 12;47(3):728-731. doi: 10.3906/sag-1508-30.
BACKGROUND/AIM: The aim of this study was to examine the prevalence of 25-hydroxyvitamin D (25(OH) vitamin D) deficiency in patients complaining of widespread musculoskeletal pain.
In this cross-sectional study, 14,925 patients (13,589 females and 1336 males; mean age: 47.0 years, range: 20-99 years) were included. Serum 25(OH) vitamin D was measured by ELISA. The patients were classified into two groups: 1) patients with vitamin D deficiency (<20 ng/mL) and 2) patients without vitamin D deficiency (>20 ng/mL).
The prevalence of vitamin D deficiency was 73.9%. A multivariate logistic regression model showed that low 25(OH) vitamin D level was associated with sex, age, and month in which 25(OH) hypovitaminosis was determined. The risk of a low 25(OH) vitamin D was level was 1.74 times higher in female patients than in males. The risk of low 25(OH) vitamin D level was highest in March during the year.
Our results indicate that vitamin D deficiency should be considered in patients with widespread musculoskeletal pain and some precautions, such as sunbathing during summer, should be recommended for patients with a risk of vitamin D deficiency.
背景/目的：本研究旨在调查主诉广泛肌肉骨骼疼痛的患者中 25-羟维生素 D（25(OH) 维生素 D）缺乏的发生率。
在这项横断面研究中，纳入了 14925 名患者（13589 名女性和 1336 名男性；平均年龄：47.0 岁，范围：20-99 岁）。通过 ELISA 法检测血清 25(OH) 维生素 D。患者被分为两组：1）维生素 D 缺乏症患者（<20ng/mL）和 2）维生素 D 不缺乏症患者（>20ng/mL）。
维生素 D 缺乏症的患病率为 73.9%。多变量逻辑回归模型显示，低 25(OH) 维生素 D 水平与性别、年龄和测定 25(OH) 维生素 D 缺乏症的月份有关。女性患者发生低 25(OH) 维生素 D 的风险是男性的 1.74 倍。在一年中的 3 月，发生低 25(OH) 维生素 D 水平的风险最高。
我们的研究结果表明，对于主诉广泛肌肉骨骼疼痛的患者，应考虑维生素 D 缺乏症，并建议维生素 D 缺乏风险较高的患者在夏季进行日光浴等预防措施。
