• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

维生素 D 补充对脑卒中患者下肢运动功能和步行能力的影响。

Effect of vitamin D supplementation on lower extremity motor function and ambulation in stroke patients.

机构信息

Department of Physical Medicine and Rehabilitation, Gazi University Faculty of Medicine, Ankara, Turkey

出版信息

Turk J Med Sci. 2021 Jun 28;51(3):1413-1419. doi: 10.3906/sag-2010-287.

DOI:10.3906/sag-2010-287
PMID:33705638
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8283454/
Abstract

BACKGROUND/AIM: The aim of this study was to investigate the effect of vitamin D supplementation on ambulation and mobility in hospitalized patients undergoing stroke rehabilitation.

MATERIALS AND METHODS

This study was conducted retrospectively between September 2020 and October 2020 at Gazi University Faculty of Medicine Physical Medicine and Rehabilitation Department. Seventy-six patients who received inpatient stroke rehabilitation treatment between May 2018 and February 2020 were included in the study. The patients were divided into two groups as those who did and did not take vitamin D supplements. Lower extremity motor function and ambulation status were compared using Brunnstrom recovery stage (lower extremity) and functional ambulation classification (FAC) scores before and after rehabilitation.

RESULTS

Thirty-nine patients received vitamin D treatment during the rehabilitation process and 37 patients did not. The two groups were similar in terms of age, sex, time since stroke, stroke type, comorbid diseases, nutritional status, rehabilitation duration, and FAC and Brunnstrom scores before rehabilitation (p > 0.05). At the end of rehabilitation, the changes in FAC and Brunnstrom scores were higher in patients receiving vitamin D supplementation (p = 0.005 and p = 0.018). The change in FAC and Brunnstrom scores in patients who were undergoing rehabilitation for the first time and/or in the first 3 months after stroke was higher in the group receiving vitamin D supplementation compared with the group not receiving vitamin D (p < 0.05). In patients who were not within the first 3 months after stroke, vitamin D treatment did not affect FAC and Brunnstrom scores.

CONCLUSION

Vitamin D supplementation may increase the success of rehabilitation therapy in patients during the first 3 months poststroke.

摘要

背景/目的:本研究旨在探讨维生素 D 补充对接受脑卒中康复治疗的住院患者步行和活动能力的影响。

材料和方法

本研究于 2020 年 9 月至 10 月在加济大学医学院物理医学与康复科进行,回顾性分析 2018 年 5 月至 2020 年 2 月期间接受住院脑卒中康复治疗的 76 例患者。根据是否服用维生素 D 补充剂,将患者分为两组。康复前后采用 Brunnstrom 恢复阶段(下肢)和功能性步行分类(FAC)评分比较下肢运动功能和步行状态。

结果

39 例患者在康复过程中接受了维生素 D 治疗,37 例患者未接受。两组患者在年龄、性别、脑卒中发病时间、脑卒中类型、合并症、营养状况、康复时间、康复前 FAC 和 Brunnstrom 评分方面无差异(p>0.05)。康复结束时,接受维生素 D 补充的患者 FAC 和 Brunnstrom 评分的变化更高(p=0.005 和 p=0.018)。首次接受康复治疗和/或脑卒中后 3 个月内的患者,接受维生素 D 补充的患者 FAC 和 Brunnstrom 评分变化更高,与未接受维生素 D 补充的患者相比差异有统计学意义(p<0.05)。在脑卒中后 3 个月内的患者中,维生素 D 治疗并未影响 FAC 和 Brunnstrom 评分。

结论

维生素 D 补充可能会增加脑卒中后前 3 个月患者康复治疗的成功率。

相似文献

1
Effect of vitamin D supplementation on lower extremity motor function and ambulation in stroke patients.维生素 D 补充对脑卒中患者下肢运动功能和步行能力的影响。
Turk J Med Sci. 2021 Jun 28;51(3):1413-1419. doi: 10.3906/sag-2010-287.
2
Mirror therapy enhances lower-extremity motor recovery and motor functioning after stroke: a randomized controlled trial.镜像疗法可促进脑卒中后下肢运动功能恢复:一项随机对照试验。
Arch Phys Med Rehabil. 2007 May;88(5):555-9. doi: 10.1016/j.apmr.2007.02.034.
3
A randomized, double-blind study to assess if vitamin D treatment affects the outcomes of rehabilitation and balance in hemiplegic patients.一项随机双盲研究,旨在评估维生素D治疗是否会影响偏瘫患者的康复和平衡结果。
J Phys Ther Sci. 2018 Jun;30(6):874-878. doi: 10.1589/jpts.30.874. Epub 2018 Jun 12.
4
A systematic review examining the effect of vitamin D supplementation on functional outcomes post-stroke.一项系统评价研究了维生素 D 补充剂对中风后功能结局的影响。
Clin Rehabil. 2023 Nov;37(11):1451-1466. doi: 10.1177/02692155231174599. Epub 2023 May 11.
5
Clinical characteristics affecting motor recovery and ambulation in stroke patients.影响中风患者运动恢复和步行能力的临床特征。
J Phys Ther Sci. 2017 Feb;29(2):216-220. doi: 10.1589/jpts.29.216. Epub 2017 Feb 24.
6
The effect of mirror therapy on lower extremity motor function and ambulation in post-stroke patients: A prospective, randomized-controlled study.镜像疗法对脑卒中后患者下肢运动功能及步行能力的影响:一项前瞻性随机对照研究。
Turk J Phys Med Rehabil. 2020 Mar 9;66(2):154-160. doi: 10.5606/tftrd.2020.2719. eCollection 2020 Jun.
7
Effectiveness of mirror therapy on lower extremity motor recovery, balance and mobility in patients with acute stroke: A randomized sham-controlled pilot trial.镜像疗法对急性中风患者下肢运动恢复、平衡和活动能力的有效性:一项随机假对照试验。
Ann Indian Acad Neurol. 2013 Oct;16(4):634-9. doi: 10.4103/0972-2327.120496.
8
Utility of the Revised Version of the Ability for Basic Movement Scale in Predicting Ambulation during Rehabilitation in Poststroke Patients.修订版基本运动能力量表在预测脑卒中患者康复期间步行能力中的应用
J Stroke Cerebrovasc Dis. 2017 Aug;26(8):1663-1669. doi: 10.1016/j.jstrokecerebrovasdis.2017.02.021. Epub 2017 May 31.
9
The effect of balance training on motor recovery and ambulation after stroke: a randomized controlled trial.平衡训练对脑卒中后运动恢复及步行能力的影响:一项随机对照试验。
Eur J Phys Rehabil Med. 2008 Mar;44(1):19-25.
10
Vitamin D Supplementation and Post-Stroke Rehabilitation: A Randomized, Double-Blind, Placebo-Controlled Trial.维生素 D 补充与卒中后康复:一项随机、双盲、安慰剂对照试验。
Nutrients. 2019 Jun 7;11(6):1295. doi: 10.3390/nu11061295.

引用本文的文献

1
Impact of vitamin D supplementation on post-stroke rehabilitation outcomes: A systematic review and meta-analysis.维生素D补充剂对中风后康复结局的影响:一项系统评价和荟萃分析。
Narra J. 2025 Aug;5(2):e1848. doi: 10.52225/narra.v5i2.1848. Epub 2025 Apr 28.
2
Efficacy of Oral Supplementation with Cholecalciferol Versus Calcifediol in Patients with Hypovitaminosis D After Stroke.中风后维生素D缺乏症患者口服补充胆钙化醇与骨化二醇的疗效比较
Nutrients. 2025 Mar 15;17(6):1035. doi: 10.3390/nu17061035.
3
The Effect of Vitamin D Supplementation on Functional Outcomes in Patients Undergoing Rehabilitation After an Ischemic Stroke: A Prospective, Single-Blind, Randomized, Placebo-Controlled Study.

本文引用的文献

1
Prognostic utility of serum 25-hydroxyvitamin D in patients with stroke: a meta-analysis.血清 25-羟维生素 D 水平对脑卒中患者预后的预测价值:一项荟萃分析。
J Neurol. 2020 Nov;267(11):3177-3186. doi: 10.1007/s00415-019-09599-0. Epub 2019 Nov 8.
2
Vitamin D Supplementation and Post-Stroke Rehabilitation: A Randomized, Double-Blind, Placebo-Controlled Trial.维生素 D 补充与卒中后康复:一项随机、双盲、安慰剂对照试验。
Nutrients. 2019 Jun 7;11(6):1295. doi: 10.3390/nu11061295.
3
Mechanisms of vitamin D on skeletal muscle function: oxidative stress, energy metabolism and anabolic state.
维生素D补充剂对缺血性中风后接受康复治疗患者功能结局的影响:一项前瞻性、单盲、随机、安慰剂对照研究。
J Clin Med. 2025 Mar 9;14(6):1848. doi: 10.3390/jcm14061848.
4
Unlocking the Potential of Vitamin D: A Comprehensive Exploration of Its Role in Neurological Health and Diseases.释放维生素D的潜力:对其在神经健康与疾病中作用的全面探索
Biology (Basel). 2025 Mar 10;14(3):280. doi: 10.3390/biology14030280.
5
25-Hydroxyvitamin D Levels and Vitamin D3 Supplementation During Postacute Spinal Cord Injury Rehabilitation.急性脊髓损伤康复期间的25-羟维生素D水平及维生素D3补充
Top Spinal Cord Inj Rehabil. 2024 Fall;30(4):24-34. doi: 10.46292/sci24-00024. Epub 2024 Nov 28.
6
Association between Vitamin D and Short-Term Functional Outcomes in Acute Ischemic Stroke.维生素 D 与急性缺血性脑卒中短期功能结局的关系。
Nutrients. 2023 Nov 29;15(23):4957. doi: 10.3390/nu15234957.
7
Vitamin D: Can Gender Medicine Have a Role?维生素D:性别医学能发挥作用吗?
Biomedicines. 2023 Jun 19;11(6):1762. doi: 10.3390/biomedicines11061762.
8
A systematic review examining the effect of vitamin D supplementation on functional outcomes post-stroke.一项系统评价研究了维生素 D 补充剂对中风后功能结局的影响。
Clin Rehabil. 2023 Nov;37(11):1451-1466. doi: 10.1177/02692155231174599. Epub 2023 May 11.
9
Vitamin D3 and Ischemic Stroke: A Narrative Review.维生素D3与缺血性卒中:一项叙述性综述
Antioxidants (Basel). 2022 Oct 27;11(11):2120. doi: 10.3390/antiox11112120.
10
The Role of Vitamin D in Stroke Prevention and the Effects of Its Supplementation for Post-Stroke Rehabilitation: A Narrative Review.维生素 D 在预防中风中的作用及其在中风后康复中的补充效果:叙事性综述。
Nutrients. 2022 Jul 4;14(13):2761. doi: 10.3390/nu14132761.
维生素 D 对骨骼肌功能的作用机制:氧化应激、能量代谢和合成代谢状态。
Eur J Appl Physiol. 2019 Apr;119(4):825-839. doi: 10.1007/s00421-019-04104-x. Epub 2019 Mar 4.
4
Global, Regional, and Country-Specific Lifetime Risks of Stroke, 1990 and 2016.全球、区域和国家特定人群终生罹患中风的风险,1990 年和 2016 年。
N Engl J Med. 2018 Dec 20;379(25):2429-2437. doi: 10.1056/NEJMoa1804492.
5
The Role of Vitamin D in Brain Health: A Mini Literature Review.维生素D在脑健康中的作用:一篇小型文献综述
Cureus. 2018 Jul 10;10(7):e2960. doi: 10.7759/cureus.2960.
6
A randomized, double-blind study to assess if vitamin D treatment affects the outcomes of rehabilitation and balance in hemiplegic patients.一项随机双盲研究,旨在评估维生素D治疗是否会影响偏瘫患者的康复和平衡结果。
J Phys Ther Sci. 2018 Jun;30(6):874-878. doi: 10.1589/jpts.30.874. Epub 2018 Jun 12.
7
Vitamin D Supplementation Seems to Improve Fibromyalgia Symptoms: Preliminary Results.补充维生素D似乎可改善纤维肌痛症状:初步结果
Isr Med Assoc J. 2018 Jun;20(6):379-381.
8
Decrement of Serum Vitamin D Level After Stroke.中风后血清维生素D水平的降低
Ann Rehabil Med. 2017 Dec;41(6):944-950. doi: 10.5535/arm.2017.41.6.944. Epub 2017 Dec 28.
9
Prevalence and risk factors for vitamin D deficiency in patients with widespread musculoskeletal pain.广泛性肌肉骨骼疼痛患者维生素 D 缺乏的患病率和危险因素。
Turk J Med Sci. 2017 Jun 12;47(3):728-731. doi: 10.3906/sag-1508-30.
10
Role of Vitamin D in the Outcome of Ischemic Stroke- A Randomized Controlled Trial.维生素D在缺血性脑卒中结局中的作用——一项随机对照试验
J Clin Diagn Res. 2017 Feb;11(2):CC06-CC10. doi: 10.7860/JCDR/2017/24299.9346. Epub 2017 Feb 1.