Albu Jeanine B, Sohler Nancy, Li Rui, Li Xuan, Young Edwin, Gregg Edward W, Ross-Degnan Dennis
Division of Endocrinology, Diabetes and Bone Disease and Division of General Medicine, Department of Medicine, Mount Sinai St. Luke's and Mount Sinai West Hospitals, Icahn School of Medicine at Mount Sinai, New York, NY
Sophie Davis School of Biomedical Education/CUNY Medical School of the City College of New York, New York, NY.
Diabetes Care. 2017 Aug;40(8):1058-1064. doi: 10.2337/dc16-2133. Epub 2017 Jun 15.
To determine the impact of a health system-wide primary care diabetes management system, which included targeted guidelines for type 2 diabetes (T2DM) and prediabetes (dysglycemia) screening, on detection of previously undiagnosed dysglycemia cases.
Intervention included electronic health record (EHR)-based decision support and standardized providers and staff training for using the American Diabetes Association guidelines for dysglycemia screening. Using EHR data, we identified 40,456 adults without T2DM or recent screening with a face-to-face visit (March 2011-December 2013) in five urban clinics. Interrupted time series analyses examined the impact of the intervention on trends in three outcomes: ) monthly proportion of eligible patients receiving dysglycemia testing, ) two negative comparison conditions (dysglycemia testing among ineligible patients and cholesterol screening), and ) yield of undiagnosed dysglycemia among those tested.
Baseline monthly proportion of eligible patients receiving testing was 7.4-10.4%. After the intervention, screening doubled (mean increase + 11.0% [95% CI 9.0, 13.0], proportion range 18.6-25.3%). The proportion of ineligible patients tested also increased (+5.0% [95% CI 3.0, 8.0]) with no concurrent change in cholesterol testing (+0% [95% CI -0.02, 0.05]). About 59% of test results in eligible patients showed dysglycemia both before and after the intervention.
Implementation of a policy for systematic dysglycemia screening including formal training and EHR templates in urban academic primary care clinics resulted in a doubling of appropriate testing and the number of patients who could be targeted for treatment to prevent or delay T2DM.
确定一个全卫生系统的初级保健糖尿病管理系统的影响,该系统包括2型糖尿病(T2DM)和糖尿病前期(血糖异常)筛查的针对性指南,对未诊断的血糖异常病例检测的影响。
干预措施包括基于电子健康记录(EHR)的决策支持以及针对使用美国糖尿病协会血糖异常筛查指南的标准化医护人员培训。利用EHR数据,我们在五家城市诊所中识别出40456名无T2DM或近期未进行面对面筛查的成年人(2011年3月至2013年12月)。中断时间序列分析考察了干预措施对三个结果趋势的影响:(1)接受血糖异常检测的合格患者的月度比例;(2)两个阴性对照条件(不合格患者的血糖异常检测和胆固醇筛查);(3)检测者中未诊断的血糖异常的检出率。
基线时接受检测的合格患者的月度比例为7.4%至10.4%。干预后,筛查增加了一倍(平均增加+11.0%[95%CI 9.0, 13.0],比例范围为18.6%至25.3%)。接受检测的不合格患者的比例也有所增加(+5.0%[95%CI 3.0, 8.0]),而胆固醇检测没有同时变化(+0%[95%CI -0.02, 0.05])。干预前后,合格患者中约59%的检测结果显示血糖异常。
在城市学术初级保健诊所实施包括正规培训和EHR模板在内的系统性血糖异常筛查政策,使适当检测增加了一倍,以及可针对其进行治疗以预防或延缓T2DM的患者数量增加。