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本文引用的文献

1
Pharmacological rescue of adult hippocampal neurogenesis in a mouse model of X-linked intellectual disability.在X连锁智力障碍小鼠模型中对成年海马神经发生进行药理学挽救
Neurobiol Dis. 2017 Apr;100:75-86. doi: 10.1016/j.nbd.2017.01.003. Epub 2017 Jan 12.
2
Oligophrenin-1 regulates number, morphology and synaptic properties of adult-born inhibitory interneurons in the olfactory bulb.少突神经胶质细胞蛋白-1调节嗅球中成年新生抑制性中间神经元的数量、形态和突触特性。
Hum Mol Genet. 2016 Dec 1;25(23):5198-5211. doi: 10.1093/hmg/ddw340.
3
Fasudil treatment in adult reverses behavioural changes and brain ventricular enlargement in Oligophrenin-1 mouse model of intellectual disability.法舒地尔治疗可逆转智障少突胶质细胞髓鞘糖蛋白-1小鼠模型中的行为变化和脑室扩大。
Hum Mol Genet. 2016 Jun 1;25(11):2314-2323. doi: 10.1093/hmg/ddw102. Epub 2016 May 4.
4
Paradox of pattern separation and adult neurogenesis: A dual role for new neurons balancing memory resolution and robustness.模式分离与成体神经发生的悖论：新生神经元在平衡记忆分辨率和稳健性方面的双重作用。
Neurobiol Learn Mem. 2016 Mar;129:60-8. doi: 10.1016/j.nlm.2015.10.013. Epub 2015 Nov 6.
5
Lack of the presynaptic RhoGAP protein oligophrenin1 leads to cognitive disabilities through dysregulation of the cAMP/PKA signalling pathway.缺乏突触前 RhoGAP 蛋白 oligophrenin1 会通过调节 cAMP/PKA 信号通路导致认知障碍。
Philos Trans R Soc Lond B Biol Sci. 2013 Dec 2;369(1633):20130160. doi: 10.1098/rstb.2013.0160. Print 2014 Jan 5.
6
Loss of X-linked mental retardation gene oligophrenin1 in mice impairs spatial memory and leads to ventricular enlargement and dendritic spine immaturity.小鼠中X连锁智力迟钝基因少突磷脂1的缺失会损害空间记忆，并导致脑室扩大和树突棘发育不成熟。
J Neurosci. 2007 Aug 29;27(35):9439-50. doi: 10.1523/JNEUROSCI.2029-07.2007.
7
The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis.X连锁智力迟钝蛋白少突神经胶质细胞1是树突棘形态发生所必需的。
Nat Neurosci. 2004 Apr;7(4):364-72. doi: 10.1038/nn1210. Epub 2004 Mar 14.
8
The RhoGAP activity of OPHN1, a new F-actin-binding protein, is negatively controlled by its amino-terminal domain.一种新的F-肌动蛋白结合蛋白OPHN1的RhoGAP活性受其氨基末端结构域的负调控。
Mol Cell Neurosci. 2003 Aug;23(4):574-86. doi: 10.1016/s1044-7431(03)00078-2.

Adult neurogenesis in intellectual disabilities.

作者信息

Allegra Manuela, Caleo Matteo

机构信息

CNR Neuroscience Institute, G. Moruzzi, Pisa, Italy.

出版信息

Oncotarget. 2017 Jul 11;8(28):45044-45045. doi: 10.18632/oncotarget.18476.

DOI:10.18632/oncotarget.18476
PMID:28620149
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5542165/
Abstract
摘要