Silva Matheus, Carneiro Matheus, Nunes Júlio, da Silva Antônio, de Sousa Marcos
Inteventional Cardiology Department, Hospital Universitário Ciências Médicas, Belo Horizonte, 30140-073, Brazil.
Inteventional Cardiology Department, Hospital São José do Avaí, Itaperuna, 28300-000, Brazil.
F1000Res. 2015 Jul 7;4:194. doi: 10.12688/f1000research.6641.1. eCollection 2015.
: Studies have reported varied prevalence estimates of coronary artery disease (CAD) in cardiac myxoma patients. We performed a systematic review and meta-analysis of observational studies to summarize the point prevalence of CAD in adults with cardiac myxomas. : Two independent investigators searched MEDLINE and LILACS databases using the terms " ", " " and " " from inception through December 2014 for all relevant studies. We included 6 observational studies. Publication bias was evaluated through Egger's test and Trim and Fill method. A pooled estimate of CAD prevalence with corresponding 95% confidence interval (CI) was calculated based on a random-effects model. The pooled CAD prevalence in adult cardiac myxoma patients was 20.7% with low heterogeneity (I = 14.86%). : It is a matter of debate if preoperative coronary angiography must be done as a routine procedure. Although coronary disease and angiographically detectable neovascularity can alter surgical management, more studies are needed to evaluate this question.
研究报告了心脏黏液瘤患者冠状动脉疾病（CAD）的患病率估计值各不相同。我们对观察性研究进行了系统评价和荟萃分析，以总结成年心脏黏液瘤患者CAD的时点患病率。两名独立研究人员从数据库建立至2014年12月，使用“ ”、“ ”和“ ”等检索词在MEDLINE和LILACS数据库中检索所有相关研究。我们纳入了6项观察性研究。通过Egger检验和Trim and Fill方法评估发表偏倚。基于随机效应模型计算CAD患病率的合并估计值及相应的95%置信区间（CI）。成年心脏黏液瘤患者CAD的合并患病率为20.7%，异质性较低（I² = 14.86%）。术前冠状动脉造影是否必须作为常规程序仍存在争议。虽然冠状动脉疾病和血管造影可检测到的新生血管会改变手术管理，但需要更多研究来评估这个问题。
