Sarkodie Benjamin Dabo, Botwe Benard Ohene, Adjei David Nana, Ofori Eric
Univeristy of Ghana, School of Medicine and Dentistry, P. O. Box GP 4236, Accra, Ghana.
Department of Radiography, University Ghana School of Biomedical and Allied Health Sciences, College of Health Sciences, P.O. Box KB 143, Korle Bu, Accra, Ghana.
Fertil Res Pract. 2016 May 1;2:9. doi: 10.1186/s40738-016-0022-9. eCollection 2016.
Uterine fibroids are the most common benign tumours affecting premenopausal women and are often associated with considerable hospitalization and morbidity. Literature shows virtually no study concerning the quantification of the main factors associated with uterine fibroids in Ghanaian women. The purpose of this study was to assess the main factors associated with uterine fibroid among Ghanaian women presenting for ultrasound.
A prospective cross-sectional study design was employed in this study. A total of two hundred and forty-four (244) women were consecutively evaluated from November 2011 to February 2012 using a 2-5 MHz curvilinear probe of Philips HD3 ultrasound machines at three centres in Accra using a trans-abdominal pelvic approach. Data was analysed with (SPSS) version 20.0 for windows, 2010; Chicago. The Pearson's Chi-square test was used to determine associations between selected demographic and gynaecological characteristics and uterine fibroid appearance. All tests were two-tailed and p-value of less than 0.05 was interpreted as significant.
The range, mean and standard deviation (SD) of the patients' age were 14-54 years, 31.89 years and ± 7.92 respectively. Factors that associated significantly with uterine fibroid in Ghanaian women included obesity ( = 17.3, -value = 0.001), participant's age range ( = 47.4, -value = 0.001), parity ( = -10.169, -value = 0.001), and age at last delivery ( = 34.579, -value = 0.001).
Uterine fibroid was mainly associated with women of older age group of the reproductive age than the younger age categories and also associated more with women with without children compared to those with more children. Moreover, it associated more with obese patients and patient with late age at last delivery.
子宫肌瘤是影响绝经前女性的最常见良性肿瘤，常导致大量住院治疗和发病。文献显示，几乎没有关于加纳女性子宫肌瘤相关主要因素量化的研究。本研究的目的是评估前来接受超声检查的加纳女性中与子宫肌瘤相关的主要因素。
本研究采用前瞻性横断面研究设计。2011年11月至2012年2月期间，在阿克拉的三个中心，使用飞利浦HD3超声机的2-5MHz曲线探头，通过经腹盆腔途径，对总共244名女性进行了连续评估。使用2010年芝加哥版的windows系统下的（SPSS）20.0对数据进行分析。采用Pearson卡方检验来确定选定的人口统计学和妇科特征与子宫肌瘤表现之间的关联。所有检验均为双侧检验，p值小于0.05被视为具有统计学意义。
患者年龄范围、平均值和标准差分别为14-54岁、31.89岁和±7.92。在加纳女性中，与子宫肌瘤显著相关的因素包括肥胖（χ²=17.3，p值=0.001）、参与者年龄范围（χ²=47.4，p值=0.001）、产次（χ²=-10.169，p值=0.001）和末次分娩年龄（χ²=34.579，p值=0.001）。
子宫肌瘤主要与育龄期年龄较大的女性相关，而非较年轻的年龄组，并且与未育女性相比，与多子女女性的关联更大。此外，它与肥胖患者以及末次分娩年龄较大的患者关联更大。
