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孕期从事重体力劳动与早产风险

Physically strenuous work during pregnancy and risk of preterm birth.

作者信息

Knudsen Iben Risager, Bonde Jens Peter, Petersen Sesilje Bondo

机构信息

a Department of Occupational and Environmental Medicine , Frederiksberg and Bispebjerg Hospital, University of Copenhagen , Copenhagen , Denmark.

出版信息

Arch Environ Occup Health. 2018 Jul 4;73(4):236-242. doi: 10.1080/19338244.2017.1342589. Epub 2017 Jul 10.

DOI:10.1080/19338244.2017.1342589
PMID:28622105
Abstract

The aim of the study was to examine the risk of preterm birth following physically strenuous work during pregnancy. We included 343 pregnant women referred to an occupational medical clinic. Data on preterm birth and covariates were retrieved from the Danish Birth Registry. Risk estimates were computed by logistic regression using a population sample of gainfully employed women as reference (n = 345,915). The risk of preterm birth was increased in women lifting heavy loads during pregnancy (OR 1.40, 95% CI [0.88, 2.23]) but not in women with physically strenuous work (OR 0.98, 95% CI [0.66, 1.46]). The mean gestational age in the heavy-lifting group compared to the reference group was 2.4 days shorter (95% CI [0.36, 4.41]). The study challenges earlier reassuring findings as heavy-lifting pregnant women had a reduced gestational age, indicating a possibility of increased risk of preterm birth.

摘要

该研究的目的是调查孕期从事高强度体力劳动后早产的风险。我们纳入了343名转诊至职业医疗诊所的孕妇。早产及协变量的数据取自丹麦出生登记处。风险估计通过逻辑回归计算得出,以有酬就业女性的人群样本作为对照(n = 345,915)。孕期搬运重物的女性早产风险增加(比值比1.40,95%置信区间[0.88, 2.23]),但从事高强度体力劳动的女性则不然(比值比0.98,95%置信区间[0.66, 1.46])。与对照组相比,搬运重物组的平均孕周短2.4天(95%置信区间[0.36, 4.41])。该研究对早期令人安心的研究结果提出了质疑,因为搬运重物的孕妇孕周缩短,这表明早产风险可能增加。

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