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药师管理的退伍军人心力衰竭出院后(过渡)诊所的影响。

Impact of a Pharmacist-Managed Heart Failure Postdischarge (Bridge) Clinic for Veterans.

作者信息

Hale Genevieve M, Hassan Sonia L, Hummel Scott L, Lewis Carrie, Ratz David, Brenner Michael

机构信息

1 Nova Southeastern University College of Pharmacy, Ann Arbor, MI, USA.

2 Garden City Hospital, MI, USA.

出版信息

Ann Pharmacother. 2017 Jul;51(7):555-562. doi: 10.1177/1060028017698974. Epub 2017 Mar 9.

Abstract

BACKGROUND

Hospitals that provide early postdischarge follow-up after heart failure (HF) hospitalization tend to have lower rates of readmission. However, HF postdischarge (bridge) clinics have not been extensively evaluated.

OBJECTIVE

To assess the impact of a pharmacist-managed HF bridge clinic in a veteran population.

METHODS

HF patients hospitalized from November 2010 to August 2013 were identified. Retrospective chart review was conducted of 122 HF patients seen at bridge clinic compared with 122 randomly selected HF patients not seen at this clinic (usual care). Primary end point was 90-day all-cause readmission and death. Secondary outcomes were 30-day all-cause readmission and death, time to first postdischarge follow-up, first all-cause readmission.

RESULTS

Bridge clinic patients were at higher baseline risk of readmission and death; other characteristics were similar. 90-day death and all-cause readmission trended lower in bridge clinic patients (adjusted hazard ratio [HR] = 0.64; 95% CI = 0.40-1.02; P = 0.06). Time to first follow-up was shorter in bridge clinic patients (11 ± 6 vs 20 ± 23 days; P < 0.001); time to first all-cause readmission trended longer (40 ± 20 vs 33 ± 25days; P = 0.11). 30-day death and all-cause readmission was significantly lower in bridge clinic patients (adjusted HR = 0.44; 95% CI = 0.22-0.88; P = 0.02).

CONCLUSIONS

In veteran patients hospitalized for HF, pharmacist-managed HF bridge clinic significantly reduced the time to initial follow-up compared with usual care. Improved short-term outcomes and trend toward improvement of longer-term outcomes in bridge clinic patients was shown.

摘要

背景

心力衰竭(HF)住院后提供早期出院后随访的医院,再入院率往往较低。然而,HF出院后(过渡)诊所尚未得到广泛评估。

目的

评估药师管理的HF过渡诊所在退伍军人人群中的影响。

方法

确定2010年11月至2013年8月期间住院的HF患者。对在过渡诊所就诊的122例HF患者与122例随机选择的未在该诊所就诊的HF患者(常规治疗)进行回顾性病历审查。主要终点是90天全因再入院和死亡。次要结局是30天全因再入院和死亡、首次出院后随访时间、首次全因再入院。

结果

过渡诊所患者再入院和死亡的基线风险较高;其他特征相似。过渡诊所患者90天死亡和全因再入院呈下降趋势(调整后风险比[HR]=0.64;95%可信区间[CI]=0.40-1.02;P=0.06)。过渡诊所患者首次随访时间较短(11±6天对20±23天;P<0.001);首次全因再入院时间呈延长趋势(40±20天对33±25天;P=0.11)。过渡诊所患者30天死亡和全因再入院显著降低(调整后HR=0.44;95%CI=0.22-0.88;P=0.02)。

结论

在因HF住院的退伍军人患者中,与常规治疗相比,药师管理的HF过渡诊所显著缩短了首次随访时间。过渡诊所患者的短期结局得到改善,长期结局有改善趋势。

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