Department of Maternal and Child Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
China Center for Health Development Studies, Peking University, Beijing, China.
BMC Womens Health. 2023 Aug 31;23(1):462. doi: 10.1186/s12905-023-02594-8.
Sexual problems are common among women with pelvic floor disorders (PFD). Few studies have explored the relationship between obesity and sexual function in women with PFD. This study aimed to prove that obesity was a risk factor for worse sexual function in women with PFD, and to investigate the mediating role of menstrual irregularity.
This was a cross-sectional study involving 783 women with PFD from Shandong Province, China between June 2020 and February 2021. Female sexual function was assessed using the Pelvic Organ Prolapse/UI Sexual Questionnaire-12 (PISQ-12). Obesity was defined as BMI ≥ 28.0. Menstrual irregularity was defined as menstrual cycles ≥ 35 or menstrual cycles < 25 days. Logistic regression and multiple linear regression were employed to explore the association among obesity, menstrual irregularity and sexual function.
Obesity was associated with worse PISQ-12 scores compared with normal- weight women (mean score 28.14 ± 7.03 versus 32.75 ± 5.66, p < 0.001). After adjusting for controlling variables, women with obesity (β= -3.74, p < 0.001) and menstrual irregularity (β= -3.41, p < 0.001) had a worse sexual function. Menstrual irregularity had a mediation effect on the association between obesity and sexual function.
This study provided evidence that obesity was associated with worse sexual function in women with PFDs, and the effect of obesity on sexual function was partially mediated by menstrual irregularity. Weight control may have potential benefits for improving sexual function and preventing female sexual dysfunction. It's also important to pay attention to the menstrual cycle.
盆底功能障碍（PFD）女性常存在性功能问题。肥胖与 PFD 女性性功能之间的关系鲜有研究。本研究旨在证明肥胖是 PFD 女性性功能障碍的危险因素，并探讨月经不规律的中介作用。
这是一项 2020 年 6 月至 2021 年 2 月期间在中国山东省进行的 PFD 女性 783 例的横断面研究。采用盆腔器官脱垂/尿失禁性功能问卷-12 （PISQ-12）评估女性性功能。肥胖定义为 BMI≥28.0。月经不规律定义为月经周期≥35 天或月经周期<25 天。采用 Logistic 回归和多元线性回归探讨肥胖、月经不规律与性功能之间的关系。
与正常体重女性相比，肥胖女性的 PISQ-12 评分较低（平均得分 28.14±7.03 比 32.75±5.66，p<0.001）。调整控制变量后，肥胖（β= -3.74，p<0.001）和月经不规律（β= -3.41，p<0.001）的女性性功能更差。月经不规律对肥胖与性功能之间的关系有中介作用。
本研究提供了证据表明肥胖与 PFD 女性性功能障碍有关，肥胖对性功能的影响部分是由月经不规律介导的。控制体重可能对改善性功能和预防女性性功能障碍有潜在益处。关注月经周期也很重要。
