Gharaibeh Lubna, Sartawi Hanan, Ayyad Diana, Juma Tareq, Albassoumi Kamal, Ismail Enas
Department of Clinical Pharmacy and Bio-pharmaceutics, School of Pharmacy, University of Jordan, Amman, Jordan.
Pharmacy Department, Al-Basheer Government Hospital, Amman, Jordan.
Int J Clin Pharm. 2017 Aug;39(4):881-887. doi: 10.1007/s11096-017-0494-7. Epub 2017 Jun 16.
Background Venous thromboembolism is the most common preventable cause of hospital death. Despite that, there is still a large gap between what we know about venous thromboembolism prophylaxis and what is happening in current practice. Objective To evaluate VTE prophylaxis in Al-Basheer hospital and assess the extent of agreement of physicians' practice with the guidelines. Setting Al-Basheer governmental hospital in Jordan between January 2016 and June 2016. Method In this cross-sectional observational study, patients were randomly selected from medical and surgical wards. The need for venous thromboembolism prophylaxis was assessed according to the American College of Chest Physicians guideline (9th edition) for men and non-pregnant women, and the Royal College of Obstetricians and Gynecologists guidelines for pregnant women.
rate of agreement of venous thromboembolism prophylaxis with the guidelines. Results The total number of patients was 1030, Patients in the medical wards constituted most of the participants. The rate of concordance with the guidelines was 718/1030 (69.7%) in the total number of patients When the patients were divided into groups: those that required venous thromboembolism prophylaxis and those that did not, the rate of agreement with guidelines in the subgroup that needed prophylaxis 160/456 (35.1%) was lower than the rate in the subgroup that did not need prophylaxis 558/574 (97.2%), p value <0.001. Conclusion venous thromboembolism prophylaxis in Al-Basheer hospital is not appropriate and underused, this might be attributed to the absence of an institutional guideline.
背景 静脉血栓栓塞是医院死亡最常见的可预防原因。尽管如此，我们对静脉血栓栓塞预防的了解与当前实际做法之间仍存在很大差距。目的 评估阿尔 - 巴希尔医院的静脉血栓栓塞预防措施，并评估医生的做法与指南的符合程度。地点 2016年1月至2016年6月期间约旦的阿尔 - 巴希尔政府医院。方法 在这项横断面观察性研究中，从内科和外科病房随机选取患者。根据美国胸科医师学会指南（第9版）对男性和非妊娠女性，以及皇家妇产科学院指南对孕妇评估静脉血栓栓塞预防的必要性。
静脉血栓栓塞预防措施与指南的符合率。结果 患者总数为1030例，内科病房的患者占大多数。患者总数中与指南的符合率为718/1030（69.7%）。当将患者分为需要静脉血栓栓塞预防和不需要预防的组时，需要预防的亚组中与指南的符合率为160/456（35.1%），低于不需要预防的亚组558/574（97.2%），p值<0.001。结论 阿尔 - 巴希尔医院的静脉血栓栓塞预防措施不合适且未充分利用，这可能归因于缺乏机构指南。
