Voizard Béatrice, Lalonde Lucie, Sanchez Lilia Maria, Richard-Chesnay Johanne, David Julie, Labelle Maude, El Khoury Mona, Trop Isabelle
Centre de recherche et d'investigation des maladies du sein (CRID), Department of Radiology, Hôtel-Dieu de Montréal, Centre Hospitalier Universitaire de Montréal (CHUM), Canada.
Centre de recherche et d'investigation des maladies du sein (CRID), Department of Radiology, Hôtel-Dieu de Montréal, Centre Hospitalier Universitaire de Montréal (CHUM), Canada.
Eur J Radiol. 2017 Jul;92:124-131. doi: 10.1016/j.ejrad.2017.04.023. Epub 2017 May 6.
Lupus mastitis is an uncommon manifestation of systemic lupus erythematosus (SLE) that affects the subcutaneous fat in the breast, much like lupus panniculitis, but additionally involves the mammary gland. We report on two women for whom lupus mastitis was the initial manifestation of SLE and provide a literature review of 34 additional cases reported in the Anglo-Saxon and French literature since 1971, making this the largest review to date. Lupus mastitis (LM) can manifest clinically as subcutaneous masses that may be painful, or may present cutaneous involvement such as thickening and discolouration. The radiologic manifestations of LM are broad and include calcifications, masses and asymmetries. Most often, excluding malignancy requires percutaneous biopsy, with histologic findings that are virtually pathognomonic for SLE. Thus, surgery is avoided and medical management can begin, antimalarial drugs and corticosteroids in most cases.
狼疮性乳腺炎是系统性红斑狼疮（SLE）的一种罕见表现，它会影响乳房的皮下脂肪，与狼疮性脂膜炎很相似，但还会累及乳腺。我们报告了两名女性患者，狼疮性乳腺炎是她们SLE的首发表现，并对自1971年以来盎格鲁 - 撒克逊语和法语文献中报道的另外34例病例进行了文献综述，这是迄今为止规模最大的综述。狼疮性乳腺炎（LM）临床上可表现为可能疼痛的皮下肿块，或出现皮肤受累，如增厚和变色。LM的放射学表现多种多样，包括钙化、肿块和不对称。通常，排除恶性肿瘤需要经皮活检，其组织学表现实际上对SLE具有诊断意义。因此，应避免手术，多数情况下可开始药物治疗，使用抗疟药和皮质类固醇。
