Lee Kwang Min, Park Ji Young, Nam Eon Jeong, Kim Won Hwa, Kim Hye Jung
J Korean Soc Radiol. 2024 Nov;85(6):1215-1220. doi: 10.3348/jksr.2024.0041. Epub 2024 Nov 15.
Lupus mastitis is a presentation of lupus panniculitis that involves subcutaneous fat in patients with systemic lupus erythematosus (SLE). Moreover, lupus mastitis is a rare condition that typically presents as a palpable breast mass. Here, we report the case of a 29-year-old woman with a prior diagnosis of SLE who presented with palpable lumps in both breasts. Imaging studies were performed, and mammography revealed extensive and bizarre calcifications, mainly in the retromammary area. US revealed large irregular calcifications with posterior shadowing, and breast MRI images exhibited diffuse irregular persistent rim enhancement in the retromammary area. An US-guided biopsy was performed to differentiate the condition from breast cancer and confirmed the diagnosis of fat necrosis, consistent with the pathological characteristics of lupus mastitis. Herein, we present a case of lupus mastitis, an unusual clinical manifestation of SLE, and discuss the clinical, pathological, and imaging findings supporting the diagnosis and the differential diagnosis.
狼疮性乳腺炎是狼疮性脂膜炎的一种表现形式，累及系统性红斑狼疮（SLE）患者的皮下脂肪。此外，狼疮性乳腺炎是一种罕见病症，通常表现为可触及的乳腺肿块。在此，我们报告一例29岁女性病例，该患者先前诊断为SLE，双侧乳房出现可触及的肿块。进行了影像学检查，乳房X线摄影显示广泛且形态怪异的钙化，主要位于乳腺后区域。超声显示大的不规则钙化伴有后方声影，乳腺MRI图像显示乳腺后区域弥漫性不规则持续性边缘强化。进行了超声引导下活检以鉴别该病症与乳腺癌，并确诊为脂肪坏死，与狼疮性乳腺炎的病理特征相符。在此，我们呈现一例狼疮性乳腺炎病例，这是SLE一种不寻常的临床表现，并讨论支持诊断及鉴别诊断的临床、病理和影像学表现。
