高功能精神分裂症患者中保留的面部情感知觉的神经相关物。
Neural correlates of preserved facial affect perception in high functioning schizophrenia.
机构信息
Northwestern University Feinberg School of Medicine, Department of Psychiatry and Behavioral Sciences, 710 N Lake Shore Drive, Chicago, IL 60611, USA.
University of Minnesota, Twin Cities, Department of Psychology, 75 East River Parkway, Minneapolis, MN 55455, USA.
出版信息
Psychiatry Res Neuroimaging. 2017 Aug 30;266:83-85. doi: 10.1016/j.pscychresns.2017.06.002. Epub 2017 Jun 3.
Individuals with 'high functioning' schizophrenia (HF-SCZ) may have preserved facial affect perception (FAP) compared to individuals with 'low functioning' schizophrenia (LF-SCZ). The neural mechanisms supporting preserved FAP in HF-SCZ have yet to be evaluated. This study compared brain activation during FAP performance in HF-SCZ, LF-SCZ, and controls. Results demonstrated greater activation in the precuneus in CON compared to both SCZ groups, while HF-SCZ activated this region intermediate to controls and LF-SCZ. These preliminary findings suggest greater precuneus activation may be related to preserved FAP in HF-SCZ compared to LF-SCZ, though future research is needed to further evaluate differences between groups.
与“低功能”精神分裂症（LF-SCZ）患者相比，“高功能”精神分裂症（HF-SCZ）患者的面部情感感知（FAP）可能保存完好。支持 HF-SCZ 中保存完好的 FAP 的神经机制尚未得到评估。本研究比较了 HF-SCZ、LF-SCZ 和对照组在 FAP 表现期间的大脑激活。结果表明，与 SCZ 两组相比，CON 中的楔前叶激活更大，而 HF-SCZ 则在控制组和 LF-SCZ 之间的中间区域激活该区域。这些初步发现表明，与 LF-SCZ 相比，HF-SCZ 中更大的楔前叶激活可能与 FAP 保存完好有关，但需要进一步研究来进一步评估组间差异。
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