Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Department of Medicine, Far Eastern Memorial Hospital, Taipei, Taiwan.
Geroscience. 2017 Jun;39(3):261-271. doi: 10.1007/s11357-017-9983-9. Epub 2017 Jun 18.
Cytomegalovirus (CMV) is an important pathogen for both clinical and population settings. There is a growing body of research implicating CMV in multiple health outcomes across the life course. At the same time, there is mounting evidence that individuals living in poverty are more likely to be exposed to CMV and more likely to experience many of the chronic conditions for which CMV has been implicated. Further research on the causal role of CMV for health and well-being is needed. However, the strong evidence implicating CMV in type 2 diabetes, autoimmunity, cancer, cardiovascular disease, vaccination, and age-related alterations in immune function warrants clinical and public health action. This imperative is even higher among individuals living in socioeconomically disadvantaged settings and those exposed to high levels of chronic psychosocial stress.
巨细胞病毒（CMV）是临床和人群环境中的重要病原体。越来越多的研究表明，CMV 与整个生命过程中的多种健康结果有关。与此同时，越来越多的证据表明，生活贫困的人更有可能接触到 CMV，并且更有可能经历许多与 CMV 有关的慢性疾病。需要进一步研究 CMV 对健康和幸福的因果作用。然而，CMV 与 2 型糖尿病、自身免疫、癌症、心血管疾病、疫苗接种以及与年龄相关的免疫功能改变之间的强证据表明，这需要临床和公共卫生部门采取行动。对于生活在社会经济劣势环境中和长期面临慢性心理社会压力的人来说，这种必要性更高。
