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黄斑前漂浮物作为视神经炎的鉴别诊断：“静止性飞蚊症”

Prefoveal floaters as a differential diagnosis to optic neuritis: "mouches dormantes".

作者信息

Burggraaff Marloes C, de Vries-Knoppert Willemine A E J, Petzold Axel

机构信息

Neuro-Ophthalmology Expertise Centre, VU University Medical Center, Amsterdam, The Netherlands.

Department of Neuro-Ophthalmology, Moorfields Eye Hospital, City Road, London, UK.

出版信息

Acta Neurol Belg. 2017 Sep;117(3):703-705. doi: 10.1007/s13760-017-0810-y. Epub 2017 Jun 17.

DOI:10.1007/s13760-017-0810-y
PMID:28624951
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5565645/
Abstract

This case series describes a new optical coherence tomography (OCT) specific observation relevant to the differential diagnosis of patients with suspected optic neuritis. A tiny prefoveal floater, only detectable by OCT, was found responsible for the symptoms in three patients, one of whom had been referred with unilateral delayed visual evoked potentials. This case series suggests that with increased use of OCT in routine clinical care, entoptic phenomena can be demonstrated as a relevant differential diagnosis to optic neuritis. Patients should be explained the benign nature of their symptoms.

摘要

本病例系列描述了一种与疑似视神经炎患者鉴别诊断相关的光学相干断层扫描（OCT）特定观察结果。发现一个仅能通过OCT检测到的微小黄斑前漂浮物是三名患者症状的原因，其中一名患者因单侧视觉诱发电位延迟而被转诊。该病例系列表明，随着OCT在常规临床护理中的使用增加，内视现象可作为视神经炎的相关鉴别诊断被证实。应向患者解释其症状的良性性质。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8428/5565645/ce5918a4cb01/13760_2017_810_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8428/5565645/ce5918a4cb01/13760_2017_810_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8428/5565645/ce5918a4cb01/13760_2017_810_Fig1_HTML.jpg

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本文引用的文献

1
Objective assessment of symptomatic vitreous floaters using optical coherence tomography: a case report.光学相干断层扫描对有症状的玻璃体漂浮物的客观评估：病例报告。
BMC Ophthalmol. 2015 Mar 8;15:22. doi: 10.1186/s12886-015-0003-5.
2
Optical coherence tomography should be part of the routine monitoring of patients with multiple sclerosis: no.光学相干断层扫描不应作为多发性硬化症患者常规监测的一部分：否。
Mult Scler. 2014 Sep;20(10):1299-301. doi: 10.1177/1352458514541510.
3
Optical coherence tomography should be part of the routine monitoring of patients with multiple sclerosis: yes.
光学相干断层扫描应成为多发性硬化症患者常规监测的一部分：是。
Mult Scler. 2014 Sep;20(10):1296-8. doi: 10.1177/1352458514541509.
4
The investigation of acute optic neuritis: a review and proposed protocol.急性视神经炎的研究：综述与建议方案
Nat Rev Neurol. 2014 Aug;10(8):447-58. doi: 10.1038/nrneurol.2014.108. Epub 2014 Jul 8.
5
Quality control for retinal OCT in multiple sclerosis: validation of the OSCAR-IB criteria.多发性硬化症中视网膜光学相干断层扫描的质量控制：OSCAR-IB标准的验证
Mult Scler. 2015 Feb;21(2):163-70. doi: 10.1177/1352458514538110. Epub 2014 Jun 16.
6
"Floater scotoma" demonstrated on spectral-domain optical coherence tomography and caused by vitreous opacification.光谱域光学相干断层扫描显示的“飞蚊症暗点”，由玻璃体混浊引起。
Ophthalmic Surg Lasers Imaging Retina. 2013 Jul-Aug;44(4):415-8. doi: 10.3928/23258160-20130715-14.
7
Should optical coherence tomography be used to manage patients with multiple sclerosis?光学相干断层扫描是否应用于多发性硬化症患者的管理？
J Neuroophthalmol. 2012 Dec;32(4):363-71. doi: 10.1097/WNO.0b013e318261f7e7.
8
Neuro-ophthalmology.神经眼科学
Pract Neurol. 2011 Jun;11(3):191-200. doi: 10.1136/practneurol-2011-000015.
9
Nd:YAG laser posterior hyaloidotomy for the treatment of a premacular vitreous floater.钕钇铝石榴石激光后玻璃体脱离术治疗黄斑前玻璃体混浊物
Bull Soc Belge Ophtalmol. 1997;265:39-43.