Hasnaoui Jawad, Anajar Said, Tatari Mohammed, Abada Reda, Rouadi Sami, Roubal Mohammed, Mahtar Mohammed
ENT Department, Face and Neck Surgery, Hospital August, 20'1953, University Hospital Centre IBN ROCHD, Casablanca, Morocco.
Ann Med Surg (Lond). 2017 Jun 3;19:41-44. doi: 10.1016/j.amsu.2017.05.036. eCollection 2017 Jul.
Carcinosarcoma is a highly malignant tumor characterized by dual malignant histologic differentiation of epithelial and mesenchymal components. The tumor is extremely rare in the sinonasal tract, with only 13 cases reported since 1957 in the literature.
We report a case of a 55-year-old man with right-sided face pain revealed a mass in the right maxillary sinus and nasal cavity. A large incisional biopsy from the nasal cavity concluded the diagnosis of carcinosarcoma. The patient was treated with chemoradiation, but no significant effect was obtained. The patient died 4 months after initial examination.
In our case, the patient consulted late with a large tumor which darkens his prognosis. According to some authors, this histological type of tumors is known by local recurrences and its lethal metastases. Prognosis is related to location, tumor size, the invasion and stage of disease. Wide surgical excision is the treatment of choice. Radiotherapy can be discussed in inoperable cases.
This is an aggressive tumor, rapidly progressive with a poor prognosis. The management of this rare condition remains undetermined.
癌肉瘤是一种高度恶性肿瘤，其特征为上皮和间充质成分的双重恶性组织学分化。该肿瘤在鼻窦极为罕见，自1957年以来文献中仅报道了13例。
我们报告一例55岁男性，因右侧面部疼痛就诊，检查发现右侧上颌窦和鼻腔有肿物。鼻腔的一次大切口活检确诊为癌肉瘤。患者接受了放化疗，但未取得显著效果。患者在初次检查后4个月死亡。
在我们的病例中，患者就诊较晚，肿瘤较大，这使其预后不佳。据一些作者称，这种组织学类型的肿瘤以局部复发和致死性转移而闻名。预后与肿瘤位置、大小、侵袭情况及疾病分期有关。广泛手术切除是首选治疗方法。对于无法手术的病例可考虑放疗。
这是一种侵袭性肿瘤，进展迅速，预后不良。这种罕见疾病的治疗方法仍未确定。
