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β-D-水杨苷的生物合成与代谢:一种在人和植物中发挥生物学功能的新型分子。

Biosynthesis and metabolism of β-d-salicin: A novel molecule that exerts biological function in humans and plants.

作者信息

Mahdi Jassem G

机构信息

College of Medicine, Shagra University, Shaqra 11961, Saudi Arabia.

出版信息

Biotechnol Rep (Amst). 2014 Aug 28;4:73-79. doi: 10.1016/j.btre.2014.08.005. eCollection 2014 Dec.

DOI:10.1016/j.btre.2014.08.005
PMID:28626665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5466123/
Abstract

β-d-Salicin (Mahdi et al. [8]) is an interesting medicinal phytochemical that exhibits cross functions in plants and humans immunologically. This molecule (Mahdi et al. [8]) has attracted the attention of scientists in various interdisciplinary fields, including chemistry, pharmacology and medicine. The biological cross functions of β-d-salicin (Mahdi et al. [8]) serve in plant survival and healing processes salicylic acid (Pierpont [23]). Thus, this raise a question whether plant biosynthesis and human metabolism crosstalk to induce therapy molecular recognition. If so, biotechnology and bioinformatics are significant techniques for new strategies in drug development. Thus, understanding the biosynthesis, metabolism and the cross-molecular setting of recognition may encourage further discussion and research on its medicinal and biological activity virtues.

摘要

β - d - 水杨苷(马赫迪等人[8])是一种有趣的药用植物化学物质,在植物和人类中具有免疫学上的交叉功能。这种分子(马赫迪等人[8])已经吸引了包括化学、药理学和医学在内的各个跨学科领域科学家的关注。β - d - 水杨苷(马赫迪等人[8])的生物学交叉功能在植物生存和愈合过程中发挥作用,就像水杨酸一样(皮尔庞特[23])。因此,这就提出了一个问题,即植物生物合成与人类新陈代谢是否相互作用以诱导治疗性分子识别。如果是这样,生物技术和生物信息学就是药物开发新策略的重要技术。因此,了解其生物合成、代谢以及识别的跨分子机制可能会促进对其药用和生物活性优点的进一步讨论和研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3652/5466123/b08b9ad2699a/sc7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3652/5466123/8fb4e2b6b07e/sc1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3652/5466123/50e33acc3816/sc2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3652/5466123/f834a575c66b/sc3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3652/5466123/47f2485ce829/sc4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3652/5466123/016319b61909/sc5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3652/5466123/7bee15b1f545/sc6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3652/5466123/b08b9ad2699a/sc7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3652/5466123/8fb4e2b6b07e/sc1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3652/5466123/50e33acc3816/sc2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3652/5466123/f834a575c66b/sc3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3652/5466123/47f2485ce829/sc4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3652/5466123/016319b61909/sc5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3652/5466123/7bee15b1f545/sc6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3652/5466123/b08b9ad2699a/sc7.jpg

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