Gong Min, Mohan Aishwarya, Gibson Angus, Udenigwe Chibuike C
Health and Bioproducts Research Laboratory, Department of Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, NS B2N 5E3, Canada.
Biotechnol Rep (Amst). 2014 Dec 12;5:63-69. doi: 10.1016/j.btre.2014.12.003. eCollection 2015 Mar.
Plastein is a protease-induced peptide aggregate with prospective application in enhancing the nutritional quality of proteins and debittering protein hydrolysates. These properties are yet to be applied in product development possibly due to economic considerations (production cost vs. product yields). This paper reviews currently proposed mechanisms of plastein formation including condensation, transpeptidation and physical interaction of aggregating peptides. Emerging findings indicate that plastein possesses bioactivities, thereby expanding its prospective application. The role of proteases in inducing peptide interaction in plastein remains unclear. Understanding the protease function will facilitate the development of efficient proteases and scalable industrial processes for plastein production.
类蛋白是一种蛋白酶诱导的肽聚集体，在提高蛋白质营养质量和消除蛋白质水解物苦味方面具有潜在应用价值。由于经济方面的考虑（生产成本与产品产量），这些特性尚未应用于产品开发。本文综述了目前提出的类蛋白形成机制，包括聚集肽的缩合、转肽作用和物理相互作用。新出现的研究结果表明类蛋白具有生物活性，从而扩大了其潜在应用范围。蛋白酶在诱导类蛋白中肽相互作用的作用仍不清楚。了解蛋白酶的功能将有助于开发高效的蛋白酶和可扩展的类蛋白生产工业工艺。
