Walsh Erin I, Jacka Felice N, Butterworth Peter, Anstey Kaarin J, Cherbuin Nicolas
Centre for Research on Ageing, Health and Wellbeing, Australian National University, Canberra, Australia.
Food and Mood Centre, IMPACT Strategic Research Centre, Deakin University, VIC, Australia.
Heliyon. 2017 Jun 7;3(6):e00315. doi: 10.1016/j.heliyon.2017.e00315. eCollection 2017 Jun.
High blood glucose and type 2 diabetes are associated with a range of adverse health and cognitive outcomes. One factor that contributes to high blood glucose and type 2 diabetes is dietary intake. This study investigated the relationship between dietary patterns, fasting blood glucose and diabetes status in a sample of 209 participants aged 60-65. Blood plasma glucose was measured from venous blood samples. Individual Prudent and Western dietary patterns were estimated from a self-completed food frequency questionnaire. The relationship between dietary patterns, diabetes, and blood glucose was assessed via general linear model analyses controlling for age, sex, height, and total caloric intake. Results indicated that there was no association between Prudent diet and fasting blood glucose levels, or type 2 diabetes. In contrast, an individual in the upper tertile for Western dietary score had a significantly higher risk of having diabetes than an individual in the lower tertile for Western dietary score. However, there was no significant association between Western diet and fasting blood glucose. Western diet may be associated with type 2 diabetes through mechanisms beyond impacting blood plasma glucose directly. The fact that the association between Western diet and type 2 diabetes remained even when total caloric intake was controlled for highlights the need for policy and population health interventions targeting the reduction of unhealthy food consumption.
高血糖和2型糖尿病与一系列不良健康和认知结果相关。导致高血糖和2型糖尿病的一个因素是饮食摄入。本研究调查了209名60 - 65岁参与者样本中饮食模式、空腹血糖和糖尿病状态之间的关系。从静脉血样本中测量血浆葡萄糖。通过一份自我填写的食物频率问卷来估计个体的谨慎饮食模式和西方饮食模式。通过控制年龄、性别、身高和总热量摄入的一般线性模型分析来评估饮食模式、糖尿病和血糖之间的关系。结果表明,谨慎饮食与空腹血糖水平或2型糖尿病之间没有关联。相比之下,西方饮食得分处于上三分位数的个体患糖尿病的风险显著高于西方饮食得分处于下三分位数的个体。然而,西方饮食与空腹血糖之间没有显著关联。西方饮食可能通过直接影响血浆葡萄糖之外的机制与2型糖尿病相关。即使在控制了总热量摄入的情况下,西方饮食与2型糖尿病之间的关联仍然存在,这一事实凸显了针对减少不健康食品消费的政策和人群健康干预措施的必要性。