Lewis R V, Jackson P R, Ramsay L E
Br J Clin Pharmacol. 1985 Jun;19(6):826-8. doi: 10.1111/j.1365-2125.1985.tb02721.x.
The prevalence of side-effects of beta-adrenoceptor antagonists among hypertensive patients was assessed by two methods. Using visual analogue scales, scores for tired legs, cold digits and vivid dreaming were significantly higher in patients taking beta-adrenoceptor blockers than in patients not taking beta-adrenoceptor blockers. When measured by numerical scales, from 1 to 10, these symptoms showed no relation to beta-adrenoceptor blocker treatment. The visual analogue scales were more sensitive than the numerical scales because the scores were distributed more evenly over the analogue scales.
通过两种方法评估了高血压患者中β-肾上腺素能受体拮抗剂副作用的发生率。使用视觉模拟量表时，服用β-肾上腺素能受体阻滞剂的患者在腿部疲劳、手指发冷和多梦方面的得分显著高于未服用β-肾上腺素能受体阻滞剂的患者。当用1至10的数字量表测量时，这些症状与β-肾上腺素能受体阻滞剂治疗无关。视觉模拟量表比数字量表更敏感，因为分数在模拟量表上分布更均匀。
