使用视觉模拟量表对β-肾上腺素能受体阻滞剂的副作用进行量化。
Quantification of side-effects of beta-adrenoceptor blockers using visual analogue scales.
作者信息
Lewis R V, Jackson P R, Ramsay L E
出版信息
Br J Clin Pharmacol. 1984 Sep;18(3):325-30. doi: 10.1111/j.1365-2125.1984.tb02471.x.
Abstract
We have devised a series of visual analogue scales (VAS) to measure the side-effects prevalent amongst hypertensive patients taking beta-adrenoceptor blockers, and we present the results of a pilot study. These show that the method is suitable for studying side-effects and suggest that patients on beta-adrenoceptor blockers experience a greater incidence of tiredness of the legs, (P = 0.001), cold digits (P = 0.005) and vivid dreaming (P = 0.01) when compared to hypertensive patients not taking beta-adrenoceptor blockers.
摘要
我们设计了一系列视觉模拟量表（VAS）来测量服用β-肾上腺素能受体阻滞剂的高血压患者中普遍存在的副作用，并展示了一项初步研究的结果。这些结果表明该方法适用于研究副作用，且表明与未服用β-肾上腺素能受体阻滞剂的高血压患者相比，服用β-肾上腺素能受体阻滞剂的患者出现腿部疲劳（P = 0.001）、手指发冷（P = 0.005）和多梦（P = 0.01）的发生率更高。
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