Medical ICU, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Peking, People's Republic of China; Department of Critical Care Medicine, the First Affiliated Hospital of Fujian Medical University, Fuzhou, People's Republic of China.
Medical ICU, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Peking, People's Republic of China.
Chest. 2017 Sep;152(3):510-517. doi: 10.1016/j.chest.2017.06.012. Epub 2017 Jun 16.
Endotracheal intubation (EI) in ICU patients is associated with an increased risk of life-threatening adverse events due to unstable conditions, rapid deterioration, limited preparation time, and variability in the expertise of operators. The goal of this study was to compare the effect of video laryngoscopy (VL) and direct laryngoscopy (DL) in ICU patients requiring EI.
We searched for relevant studies in PubMed, Embase, and the Cochrane database from inception through January 30, 2017. Randomized controlled trials were included if they reported data on any of the predefined outcomes in ICU patients requiring EI and managed with VL or DL. Results were expressed as risk ratios (RRs) or mean differences (MDs) with accompanying 95% CIs.
Five randomized controlled trials with 1,301 patients were included. Despite better glottic visualization with VL (RR = 1.24; 95% CI, 1.07 to 1.43; P = .003), use of VL did not result in a significant increase in the first-attempt success rate (RR = 1.08; 95% CI, 0.92-1.26; P = .35) compared with DL. In addition, time to intubation (MD = 4.12 s; 95% CI, -15.86-24.09; P = .69), difficult intubation (RR = 0.72; 95% CI, 0.30-1.70; P = .45), mortality (RR = 1.02; 95% CI, 0.84-1.25; P = .83), and most other complications were similar between the VL and DL groups.
The VL technique did not increase the first-attempt success rate during EI in ICU patients compared with DL. These findings do not support routine use of VL in ICU patients.
由于患者情况不稳定、病情迅速恶化、准备时间有限以及操作者专业水平的差异,重症监护病房(ICU)患者行气管插管(EI)与危及生命的不良事件风险增加相关。本研究旨在比较在需要 EI 的 ICU 患者中,视频喉镜(VL)与直接喉镜(DL)的效果。
我们检索了从建库至 2017 年 1 月 30 日PubMed、Embase 和 Cochrane 数据库中的相关研究。如果研究报告了任何预先设定的结局数据,且纳入的 ICU 患者需要 EI,并使用 VL 或 DL 进行管理,我们则将其纳为随机对照试验。结果以风险比(RR)或均数差值(MD)表示,并附有 95%置信区间(CI)。
纳入了 5 项包含 1301 例患者的随机对照试验。尽管 VL 可更好地显示声门(RR=1.24;95%CI,1.07 至 1.43;P=0.003),但与 DL 相比,VL 并未显著提高首次尝试的成功率(RR=1.08;95%CI,0.92 至 1.26;P=0.35)。此外,VL 与 DL 组间的插管时间(MD=4.12 s;95%CI,-15.86 至 24.09;P=0.69)、困难插管(RR=0.72;95%CI,0.30 至 1.70;P=0.45)、死亡率(RR=1.02;95%CI,0.84 至 1.25;P=0.83)以及大多数其他并发症发生率均无显著差异。
与 DL 相比,VL 技术并未增加 ICU 患者 EI 时的首次尝试成功率。这些发现不支持在 ICU 患者中常规使用 VL。