支气管扩张症的诊断与管理
Diagnosis and management of bronchiectasis.
作者信息
Smith Maeve P
机构信息
Department of Medicine, Division of Pulmonary Medicine, University of Alberta, Edmonton, Alta.
出版信息
CMAJ. 2017 Jun 19;189(24):E828-E835. doi: 10.1503/cmaj.160830.
Abstract
KEY POINTS Following a diagnosis of bronchiectasis, it is important to investigate for an underlying cause. Goals of management are to suppress airway infection and inflammation, to improve symptoms and health-related quality of life. There are now validated scoring tools to help assess disease severity, which can help to stratify management. Good evidence supports the use of both exercise training and long-term macrolide therapy in long-term disease management.
摘要
要点
诊断为支气管扩张后，重要的是调查潜在病因。管理目标是抑制气道感染和炎症，改善症状及与健康相关的生活质量。现在有经过验证的评分工具来帮助评估疾病严重程度，这有助于分层管理。有力证据支持在长期疾病管理中使用运动训练和长期大环内酯类药物治疗。
相似文献
1
Diagnosis and management of bronchiectasis.支气管扩张症的诊断与管理
CMAJ. 2017 Jun 19;189(24):E828-E835. doi: 10.1503/cmaj.160830.
2
Management of bronchiectasis in adults.成人支气管扩张症的管理。
Eur Respir J. 2015 May;45(5):1446-62. doi: 10.1183/09031936.00119114. Epub 2015 Mar 18.
3
Non-cystic fibrosis bronchiectasis.非囊性纤维化性支气管扩张症。
Am J Respir Crit Care Med. 2013 Sep 15;188(6):647-56. doi: 10.1164/rccm.201303-0411CI.
4
Raising awareness of bronchiectasis in primary care: overview of diagnosis and management strategies in adults.提高初级保健中对支气管扩张症的认识：成人诊断和管理策略概述。
NPJ Prim Care Respir Med. 2017 Mar 13;27(1):18. doi: 10.1038/s41533-017-0019-9.
5
Bronchiectasis: new approaches to diagnosis and management.支气管扩张症：新的诊断和治疗方法。
Clin Chest Med. 2011 Sep;32(3):535-46. doi: 10.1016/j.ccm.2011.05.002.
6
Emerging drugs for bronchiectasis.支气管扩张症的新兴药物。
Expert Opin Emerg Drugs. 2012 Sep;17(3):361-78. doi: 10.1517/14728214.2012.702755. Epub 2012 Jul 19.
7
Bronchiectasis: an update.支气管扩张症：最新进展
Clin Respir J. 2009 Jul;3(3):126-34. doi: 10.1111/j.1752-699X.2009.00131.x.
8
[Diagnosis and treatment of bronchiectasis. Spanish Society of Pneumology and Thoracic Surgery].[支气管扩张症的诊断与治疗。西班牙肺科与胸外科协会]
Arch Bronconeumol. 2008 Nov;44(11):629-40. doi: 10.1157/13128330.
9
The use of antiinflammatory therapy and macrolides in bronchiectasis.支气管扩张症中抗炎治疗和大环内酯类药物的应用。
Clin Chest Med. 2012 Jun;33(2):371-80. doi: 10.1016/j.ccm.2012.02.001. Epub 2012 Mar 31.
10
[Pathophysiology and treatment of bronchectasis].[支气管扩张症的病理生理学与治疗]
Pneumologia. 2011 Jan-Mar;60(1):26-9.
引用本文的文献
1
Bronchiectasis-COPD Overlap Syndrome: A Comprehensive Review of its Pathophysiology and Potential Cardiovascular Implications.支气管扩张-慢性阻塞性肺疾病重叠综合征：其病理生理学及潜在心血管影响的综合综述
Ther Adv Pulm Crit Care Med. 2024 Dec 9;19:29768675241300808. doi: 10.1177/29768675241300808. eCollection 2024 Jan-Dec.
2
The characteristics and prognosis of bronchiectasis patients with airflow limitation: a prospective longitudinal study.气流受限的支气管扩张症患者的特征与预后：一项前瞻性纵向研究
BMC Pulm Med. 2024 Dec 3;24(1):599. doi: 10.1186/s12890-024-03422-x.
3
Factors influencing survival and mortality among adult Aboriginal Australians with bronchiectasis-A 10-year retrospective study.影响成年澳大利亚原住民支气管扩张症患者生存和死亡的因素——一项10年回顾性研究。
Front Med (Lausanne). 2024 May 7;11:1366037. doi: 10.3389/fmed.2024.1366037. eCollection 2024.
4
Evidence-based management guidelines for noncystic fibrosis bronchiectasis in children and adolescents.儿童和青少年非囊性纤维化支气管扩张症的循证管理指南
Clin Exp Pediatr. 2024 Sep;67(9):418-426. doi: 10.3345/cep.2023.00871. Epub 2024 Jan 23.
5
Non-cystic fibrosis bronchiectasis: A single-centre retrospective study in Johannesburg, South Africa.非囊性纤维化支气管扩张症：南非约翰内斯堡的一项单中心回顾性研究。
Afr J Thorac Crit Care Med. 2023 Nov 27;29(4):e1017. doi: 10.7196/AJTCCM.2023.v29i4.1017. eCollection 2023.
6
Microbiology sampling in non-cystic fibrosis bronchiectasis cases from northern Alberta.阿尔伯塔省北部非囊性纤维化支气管扩张症病例的微生物采样。
PLoS One. 2023 Jul 14;18(7):e0288704. doi: 10.1371/journal.pone.0288704. eCollection 2023.
7
Daily versus three-times-weekly azithromycin in Chinese patients with non-cystic fibrosis bronchiectasis: protocol for a prospective, open-label and randomised controlled trial.每日与每周三次阿奇霉素治疗中国非囊性纤维化支气管扩张症患者的前瞻性、开放标签、随机对照试验方案。
BMJ Open. 2022 Jul 8;12(7):e059186. doi: 10.1136/bmjopen-2021-059186.
8
Non-Pharmaceutical Techniques for Obstructive Airway Clearance Focusing on the Role of Oscillating Positive Expiratory Pressure (OPEP): A Narrative Review.聚焦振荡呼气正压（OPEP）作用的阻塞性气道清除非药物技术：一项叙述性综述。
Pulm Ther. 2022 Mar;8(1):1-41. doi: 10.1007/s41030-021-00178-1. Epub 2021 Dec 3.
9
Effects of Doxofylline Combined with Ceftazidime on Clinical Efficacy, Drug Safety, and Prognosis in Patients with Chronic Obstructive Pulmonary Disease Complicated with Infection.多索茶碱联合头孢他啶对慢性阻塞性肺疾病合并感染患者的临床疗效、药物安全性及预后的影响。
Med Sci Monit. 2021 Aug 18;27:e930494. doi: 10.12659/MSM.930494.
10
Association Between Non-Cystic Fibrosis Bronchiectasis and Quality of Life: A Single-Center Cross-Sectional Study.非囊性纤维化支气管扩张症与生活质量的关联：一项单中心横断面研究
Cureus. 2021 Mar 31;13(3):e14231. doi: 10.7759/cureus.14231.
本文引用的文献
1
Factors related to depression and anxiety in adults with bronchiectasis.支气管扩张症成人患者中与抑郁和焦虑相关的因素。
Neuropsychiatr Dis Treat. 2016 Nov 23;12:3005-3010. doi: 10.2147/NDT.S121147. eCollection 2016.
2
Bronchiectasis Severity Is an Independent Risk Factor for Vascular Disease in a Bronchiectasis Cohort.支气管扩张症严重程度是支气管扩张症队列中血管疾病的独立危险因素。
Chest. 2017 Feb;151(2):383-388. doi: 10.1016/j.chest.2016.09.022. Epub 2016 Oct 6.
3
Bronchiectasis and the risk of cardiovascular disease: a population-based study.支气管扩张症与心血管疾病风险：一项基于人群的研究。
Thorax. 2017 Feb;72(2):161-166. doi: 10.1136/thoraxjnl-2015-208188. Epub 2016 Aug 29.
4
Multidimensional severity assessment in bronchiectasis: an analysis of seven European cohorts.支气管扩张症的多维严重程度评估：对七个欧洲队列的分析
Thorax. 2016 Dec;71(12):1110-1118. doi: 10.1136/thoraxjnl-2016-208481. Epub 2016 Aug 11.
5
Lung transplantation for non-cystic fibrosis bronchiectasis.非囊性纤维化支气管扩张症的肺移植
Respir Med. 2016 Jun;115:60-5. doi: 10.1016/j.rmed.2016.04.007. Epub 2016 Apr 20.
6
Short-term effects of three slow expiratory airway clearance techniques in patients with bronchiectasis: a randomised crossover trial.三种缓慢呼气气道廓清技术对支气管扩张症患者的短期影响：一项随机交叉试验
Physiotherapy. 2016 Dec;102(4):357-364. doi: 10.1016/j.physio.2015.07.005. Epub 2015 Dec 1.
7
Changes in the incidence, prevalence and mortality of bronchiectasis in the UK from 2004 to 2013: a population-based cohort study.2004年至2013年英国支气管扩张症的发病率、患病率及死亡率变化：一项基于人群的队列研究。
Eur Respir J. 2016 Jan;47(1):186-93. doi: 10.1183/13993003.01033-2015. Epub 2015 Nov 5.
8
Etiology of Non-Cystic Fibrosis Bronchiectasis in Adults and Its Correlation to Disease Severity.成人非囊性纤维化支气管扩张症的病因及其与疾病严重程度的相关性
Ann Am Thorac Soc. 2015 Dec;12(12):1764-70. doi: 10.1513/AnnalsATS.201507-472OC.
9
Aetiology and clinical characteristics of patients with bronchiectasis in a Chinese Han population: A prospective study.中国汉族人群支气管扩张症患者的病因及临床特征：一项前瞻性研究。
Respirology. 2015 Aug;20(6):917-24. doi: 10.1111/resp.12574. Epub 2015 Jun 19.
10
Effects of Pulmonary Rehabilitation in Patients with Non-Cystic Fibrosis Bronchiectasis: A Retrospective Analysis of Clinical and Functional Predictors of Efficacy.非囊性纤维化支气管扩张症患者肺康复的效果：疗效的临床和功能预测因素的回顾性分析
Respiration. 2015;89(6):525-33. doi: 10.1159/000380771. Epub 2015 Apr 28.
Zotero 插件