Nygaard Håvard, Rønnestad Bent R, Hammarström Daniel, Holmboe-Ottesen Gerd, Høstmark Arne T
Department of Sport Science, Lillehammer University College, Norway.
Institute of Health and Society, Department of Community Medicine, University of Oslo, Norway.
J Sports Sci Med. 2017 Jun 1;16(2):254-263. eCollection 2017 Jun.
The purpose of the present study was to test if one bout of moderate exercise performed in either the fasted or the postprandial state affects glucose values measured over 22 hours. Twelve participants diagnosed with hyperglycemia not using antidiabetic medications underwent 3 test days in a randomized cross-over design encompassing one test day without exercise, one test day with 60 min of treadmill walking prior to breakfast, and one test day with an identical bout of exercise 30 min after the start of breakfast. Continuous glucose monitoring was performed until the next morning (>22 hours). There was no significant effect of type of test day on the area under the glucose curve for the entire 22 hours period (p = 0.111). None of the exercise interventions had a significant effect on the area under the glucose curve after breakfast, lunch or dinner. However, the postprandial exercise bout tended to decrease the area under the glucose curve after the evening meal compared to the fasted exercise bout (24.2 ± 6.2 vs. 27.6 ± 6.0 mmol·hour·L, p = 0.031). Furthermore, the postprandial exercise decreased the mean of the 10 highest glucose values measured in each individual (8.6 ± 1.9 mmol·L) over 22 hours compared to both the control day (9.3 ± 2.1 mmolL) and the day with fasted exercise (9.6 ± 1.7 mmol·L, p = 0.012 and 0.009 respectively). Postprandial exercise also decreased the glycemic variability compared to the control day (1.22 ± 0.49 vs. 1.58 ± 0.52 mmol·L, p = 0.015). We conclude that performing moderate exercise in the postprandial state after breakfast, but not in the fasted state, decreases glucose excursions during the subsequent 22 hours period in hyperglycemic individuals not using antidiabetic medications.
本研究的目的是测试在空腹或餐后状态下进行一次中等强度运动是否会影响22小时内测得的血糖值。12名被诊断为高血糖且未使用抗糖尿病药物的参与者采用随机交叉设计进行了3个测试日，包括1个无运动的测试日、1个早餐前进行60分钟跑步机步行的测试日，以及1个早餐开始后30分钟进行相同运动时长的测试日。持续进行葡萄糖监测直至次日早晨（>22小时）。在整个22小时期间，测试日类型对葡萄糖曲线下面积无显著影响（p = 0.111）。没有任何一种运动干预对早餐、午餐或晚餐后的葡萄糖曲线下面积有显著影响。然而，与空腹运动相比，餐后运动倾向于降低晚餐后的葡萄糖曲线下面积（24.2±6.2 vs. 27.6±6.0 mmol·小时·L，p = 0.031）。此外，与对照日（9.3±2.1 mmol/L）和空腹运动日（9.6±1.7 mmol·L，p分别为0.012和0.009）相比，餐后运动降低了每个个体在22小时内测得的10个最高血糖值的平均值（8.6±1.9 mmol·L）。与对照日相比，餐后运动还降低了血糖变异性（1.22±0.49 vs. 1.58±0.52 mmol·L，p = 0.015）。我们得出结论，在早餐后餐后状态下进行中等强度运动，而非在空腹状态下进行，可降低未使用抗糖尿病药物的高血糖个体在随后22小时内的血糖波动。
