Unit of Exercise Physiology, Department of Movement, Human and Health Sciences, University of Rome "Foro Italico", Piazza Lauro de Bosis 6, 00135, Rome, Italy.
Unit of Endocrinology, Department of Movement, University of Rome "Foro Italico", Piazza Lauro de Bosis 6, 00135, Rome, Italy.
Eur J Nutr. 2021 Sep;60(6):3437-3447. doi: 10.1007/s00394-021-02512-4. Epub 2021 Feb 26.
Exercise plays an important role in preventing and treating postprandial dysmetabolism. We investigated the postprandial metabolic responses to a standard lunch when a session of aerobic exercise is performed in the early postprandial phase or divided between the pre- and postprandial period.
Nine healthy volunteers consumed a standardised mixed lunch and rested for the following 3 h (Con) or performed 40 min of cycling at 65% V̇Omax after lunch (CPPEx), or two 20-min sessions, one before (SplitEx1) and the other after lunch (SplitEx2), at the same intensity.
At 1-h post-lunch, a significant reduction (P < 0.001) in glycaemia was observed for CPPEx (- 25 ± 10%) and SplitEx (- 34 ± 7%) compared to Con. Yet, a post-exercise rebound lessened the exercise effect on the glycaemic area under the curve (AUC) at 2 and 3 h. At 1 h, a significant reduction (P < 0.009) in plasma insulin (SplitEx - 53 ± 31%; CCPEx - 48 ± 20%) and C-peptide (SplitEx - 57 ± 20%; CCPEx - 47 ± 24%) was observed compared to Con. Glucose-dependent insulinotropic polypeptide (GIP) increased after the meal, without differences between conditions. Compared with SplitEx1, cortisol response was attenuated during SplitEx2 and CPPEx. At 3 hours, triglyceride AUC was significantly higher (P = 0.039) in SplitEx compared to Con (+ 19 ± 8%).
Forty minutes of postprandial exercise or 20 min of pre- and postprandial exercise are both effective at attenuating the glycaemic and insulinaemic response to a mixed lunch, while a higher lipaemia was found in the pre- and postprandrial exercise condition.
运动在预防和治疗餐后代谢紊乱方面起着重要作用。我们研究了在早期餐后阶段或在餐前和餐后阶段之间进行有氧运动时，标准午餐后的餐后代谢反应。
9 名健康志愿者食用标准化混合午餐，然后休息 3 小时（Con）或在午餐后进行 40 分钟 65% V̇Omax 的自行车运动（CPPEx），或在同一强度下进行两次 20 分钟的运动，一次在餐前（SplitEx1），另一次在午餐后（SplitEx2）。
午餐后 1 小时，CPPEx（-25±10%）和 SplitEx（-34±7%）的血糖明显降低（P<0.001）与 Con 相比。然而，运动后的反弹减轻了运动对餐后 2 小时和 3 小时血糖曲线下面积（AUC）的影响。午餐后 1 小时，与 Con 相比，血浆胰岛素（SplitEx-53±31%；CCPEx-48±20%）和 C 肽（SplitEx-57±20%；CCPEx-47±24%）显著降低（P<0.009）。进食后葡萄糖依赖性胰岛素释放肽（GIP）增加，但各条件之间无差异。与 SplitEx1 相比，在 SplitEx2 和 CPPEx 期间，皮质醇反应减弱。3 小时时，SplitEx 的甘油三酯 AUC 明显高于 Con（+19±8%，P=0.039）。
40 分钟的餐后运动或 20 分钟的餐前和餐后运动都能有效减轻混合午餐后的血糖和胰岛素反应，而在餐前和餐后运动条件下发现更高的血脂。
