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髋关节保留手术后慢性术后疼痛的预测因素及发展轨迹

Predictors and trajectories of chronic postoperative pain following hip preservation surgery.

作者信息

Sieberg Christine B, Klajn Justyna, Wong Cindy, Bowen Garrett, Simons Laura E, Millis Michael B

机构信息

1. Division of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital, Boston, MA USA.

2. Department of Psychiatry, Harvard Medical School. Boston, MA USA.

出版信息

J Hip Preserv Surg. 2017 Mar 27;4(1):45-53. doi: 10.1093/jhps/hnx003. eCollection 2017 Jan.

DOI:10.1093/jhps/hnx003
PMID:28630720
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5467405/
Abstract

Factors contributing to chronic postoperative pain (CPOP) are poorly defined in young people and developmental considerations are poorly understood. With over 5 million children undergoing surgery yearly and 25% of adults referred to chronic pain clinics identifying surgery as the antecedent, there is a need to elucidate factors that contribute to CPOP in surgical patients. The present study includes patients undergoing hip preservation surgery at a children's hospital. The HOOS and SF-12 Health Survey were administered to 614 pre-surgical patients with 421 patients completing follow-up (6-months, 1-year and 2-years post-surgery). Pain, quality of life, and functioning across time were examined for each group within the population. A three trajectory model (low pain, pain improvement and high pain) emerged indicating three categories of treatment responders. Pain trajectory groups did not differ significantly on gender, pre-surgical age, BMI, prior hip surgery, surgical type, joint congruence or Tönnis grade. The groups differed significantly from each other on pre-surgical pain, pain chronicity, quality of life and functioning. Those in the high pain and pain improvement groups endorsed having pre-surgical depression at significantly higher rates and lower pre-surgical quality of life compared to those in the low pain group ( < 0.01). Those in the high pain group reported significantly worse pre-surgical functioning compared to those in the pain improvement ( < 0.0001) and low pain groups ( < 0.0001).The results demonstrate the need for preoperative screening prior to hip preservation surgery, as there may be a subset of patients who are predisposed to chronic pain independent of hip health.

摘要

导致青少年慢性术后疼痛(CPOP)的因素尚不明确,对发育相关因素的了解也很有限。每年有超过500万儿童接受手术,在转诊至慢性疼痛诊所的成年人中,有25%将手术视为疼痛的诱因,因此有必要阐明导致手术患者发生CPOP的因素。本研究纳入了一家儿童医院接受保髋手术的患者。对614名术前患者进行了髋关节功能评分(HOOS)和SF-12健康调查,其中421名患者完成了随访(术后6个月、1年和2年)。对总体人群中的每组患者随时间的疼痛、生活质量和功能进行了检查。出现了一个三轨迹模型(低疼痛、疼痛改善和高疼痛),表明存在三类治疗反应者。疼痛轨迹组在性别、术前年龄、体重指数、既往髋关节手术史、手术类型、关节吻合度或托尼斯分级方面无显著差异。这些组在术前疼痛、疼痛慢性化程度、生活质量和功能方面存在显著差异。与低疼痛组相比,高疼痛组和疼痛改善组的患者术前抑郁发生率显著更高,术前生活质量更低(<0.01)。与疼痛改善组(<0.0001)和低疼痛组(<0.0001)相比,高疼痛组患者报告术前功能明显更差。结果表明,在保髋手术前需要进行术前筛查,因为可能存在一部分患者,他们易患慢性疼痛,而与髋关节健康无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91dd/5467405/5cec6a6e8d5e/hnx003f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91dd/5467405/5cec6a6e8d5e/hnx003f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91dd/5467405/5cec6a6e8d5e/hnx003f1.jpg

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